Literature DB >> 12679059

One step further towards real high-throughput functional genomics.

Ronald Oude Elferink1.   

Abstract

In a recent paper by Michiels et al. an important step was made towards genuine high throughput functional genomics. The authors produced an arrayed adenoviral library containing >120000 cDNAs isolated from human placenta. This library can be used for arrayed transduction of cell lines in phenotypic assays and to screen for genes involved in the induction of any phenotype for which a robust high-throughput assay can be designed.

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Year:  2003        PMID: 12679059     DOI: 10.1016/S0167-7799(03)00029-5

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  2 in total

Review 1.  The application of FAST-NMR for the identification of novel drug discovery targets.

Authors:  Robert Powers; Kelly A Mercier; Jennifer C Copeland
Journal:  Drug Discov Today       Date:  2008-02       Impact factor: 7.851

2.  Solution structure and function of YndB, an AHSA1 protein from Bacillus subtilis.

Authors:  Jaime L Stark; Kelly A Mercier; Geoffrey A Mueller; Thomas B Acton; Rong Xiao; Gaetano T Montelione; Robert Powers
Journal:  Proteins       Date:  2010-12
  2 in total

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