Literature DB >> 12677206

Diabetic Retinopathy and the NMDA Receptor.

Sylvia B. Smith.   

Abstract

Diabetic retinopathy is a major sight-threatening disease and is a leading cause of blindness. There is an emerging body of evidence that suggests that neuronal changes are an early phenomenon in the diabetic retina and that several cell types are affected, including the ganglion cells. The degeneration of these cells is thought to occur via overstimulation of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptor. Characteristic features of the normal mammalian retina and of the diabetic retina, and the involvement of NMDA receptors in diabetic retinopathy, are discussed. (c) 2002 Prous Science. All rights reserved.

Entities:  

Year:  2002        PMID： 12677206      PMCID： PMC3773688          DOI： 10.1358/dnp.2002.15.4.840055

Source DB:  PubMed          Journal:  Drug News Perspect        ISSN： 0214-0934


  62 in total

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Journal:  J Clin Invest       Date:  1998-08-15       Impact factor: 14.808

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Journal:  Brain Res       Date:  1996-03-04       Impact factor: 3.252

10.  Color vision defects in early diabetic retinopathy.

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  7 in total

Review 1.  The role of Optical Coherence Tomography Angiography to detect early microvascular changes in Diabetic Retinopathy: a systematic review.

Authors:  Filipa Palma; Pedro Camacho
Journal:  J Diabetes Metab Disord       Date:  2021-09-16

Review 2.  Retinal Glutamate Neurotransmission: From Physiology to Pathophysiological Mechanisms of Retinal Ganglion Cell Degeneration.

Authors:  Isabella Boccuni; Richard Fairless
Journal:  Life (Basel)       Date:  2022-04-25

3.  Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced Sprague-Dawley rats.

Authors:  Xiaoping Yu; Zhaoxia Xu; Mantian Mi; Hongxia Xu; Jundong Zhu; Na Wei; Ka Chen; Qianyong Zhang; Kaihong Zeng; Jian Wang; Fang Chen; Yong Tang
Journal:  Neurochem Res       Date:  2007-08-31       Impact factor: 3.996

4.  Systemic Administration of an Apelin Receptor Agonist Prevents NMDA-Induced Loss of Retinal Neuronal Cells in Mice.

Authors:  Fumiya Shibagaki; Yuki Ishimaru; Akihide Sumino; Akiko Yamamuro; Yasuhiro Yoshioka; Sadaaki Maeda
Journal:  Neurochem Res       Date:  2020-01-01       Impact factor: 3.996

5.  The Susceptibility of Retinal Ganglion Cells to Glutamatergic Excitotoxicity Is Type-Specific.

Authors:  Ian Christensen; Bo Lu; Ning Yang; Kevin Huang; Ping Wang; Ning Tian
Journal:  Front Neurosci       Date:  2019-03-15       Impact factor: 4.677

6.  Implications of Diabetes-Induced Altered Metabolites on Retinal Neurodegeneration.

Authors:  Dalia I Aldosari; Ajamaluddin Malik; Abdullah S Alhomida; Mohammad S Ola
Journal:  Front Neurosci       Date:  2022-07-13       Impact factor: 5.152

7.  Protective Effect of Palm Oil-Derived Tocotrienol-Rich Fraction Against Retinal Neurodegenerative Changes in Rats with Streptozotocin-Induced Diabetic Retinopathy.

Authors:  Muhammad Zulfiqah Sadikan; Nurul Alimah Abdul Nasir; Renu Agarwal; Nafeeza Mohd Ismail
Journal:  Biomolecules       Date:  2020-04-05
  7 in total

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