Literature DB >> 12673000

Three new ingol diterpenes from Euphorbia nivulia: evaluation of cytotoxic activity.

Veluri Ravikanth1, Vanimireddy Lakshmi Niranjan Reddy, Adelli Vijender Reddy, Kodela Ravinder, Tadikamalla Prabhakar Rao, Tejomoorty Siva Ram, Kondapi Anand Kumar, Diwan Prakesh Vamanarao, Yenamandra Venkateswarlu.   

Abstract

The latex of Euphorbia nivulia afforded three new ingol diterpenes, 3-acetyl-8-methoxyl-7-angolyl-12-hydroxylingol (7), 3,12-diacetyl-7-hydroxy-8-methoxylingol (8), and 3,12-diacetyl-7-angolyl-8-hydroxylingol (9) along with five known ingol diterpenes 2-6 and a known triterpene cyclonivulinol (1). Their structures were established by means of spectroscopic analysis. Diterpenes 2-9 were evaluated for their cytotoxic activity.

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Year:  2003        PMID: 12673000     DOI: 10.1248/cpb.51.431

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  4 in total

1.  Induction of apoptosis in leukemia cell lines by Linum persicum and Euphorbia cheiradenia.

Authors:  Zahra Amirghofran; Masoud Bahmani; Abbas Azadmehr; Katayoun Javidnia
Journal:  J Cancer Res Clin Oncol       Date:  2006-02-14       Impact factor: 4.553

2.  Antinociceptive, muscle relaxant and sedative activities of gold nanoparticles generated by methanolic extract of Euphorbia milii.

Authors:  Nazar Ul Islam; Ibrahim Khan; Abdur Rauf; Naveed Muhammad; Muhammad Shahid; Mohammad Raza Shah
Journal:  BMC Complement Altern Med       Date:  2015-05-29       Impact factor: 3.659

3.  Investigation of Euphorbia nivulia-HAM for Enzyme Inhibition Potential in Relation to the Phenolic and Flavonoid Contents and Radical Scavenging Activity.

Authors:  Muhammad Younus; Muhammad Mohtasheem-Ul-Hasan; Shakeel Ijaz; Muhammad Kamran; Ambreen Maqsood; Bushra Saddique; Uzair Nisar; Muhammad Ashraf; Eman A Mahmoud; Ahmed M El-Sabrout; Hosam O Elansary
Journal:  Life (Basel)       Date:  2022-02-21

Review 4.  Pharmacological Potential of Lathyrane-Type Diterpenoids from Phytochemical Sources.

Authors:  Fátima Vela; Abdellah Ezzanad; Alan Christy Hunter; Antonio José Macías-Sánchez; Rosario Hernández-Galán
Journal:  Pharmaceuticals (Basel)       Date:  2022-06-23
  4 in total

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