| Literature DB >> 12672498 |
Cheryl C Hsia1, William McGinnis.
Abstract
Functional assays in Drosophila melanogaster with orthologous transcription factors from other species suggest that changes in the protein-coding sequence may play a larger role in the evolution of transcription factor pathways than was previously believed. Interestingly, recent studies provide evidence that changes in transcription factor protein sequence can affect the regulation of only a subset of target genes, even in the same cells of a developing animal.Entities:
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Year: 2003 PMID: 12672498 DOI: 10.1016/s0959-437x(03)00017-0
Source DB: PubMed Journal: Curr Opin Genet Dev ISSN: 0959-437X Impact factor: 5.578