Literature DB >> 12668084

Measurements of sub-nanomolar concentrations of unmetabolised folic acid in serum.

Mary Rose Sweeney1, Joseph McPartlin, Donald George Weir, John Martin Scott.   

Abstract

We describe a combined HPLC/microbiological assay procedure for the sub-nanomolar analysis of unmetabolised folic acid (pteroylglutamate) in human serum. This metabolically unaltered form of the vitamin arises following the consumption of folic acid either in supplemental form or in fortified foods. Following HPLC separation of folic acid from other folate derivatives the folic acid fraction was concentrated by C(18) Sep-Pak cartridges and assayed by Lactobacillus casei microbiological assay. The present assay allows the quantitation and kinetic analysis of the effects of consumption of folic acid.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12668084     DOI： 10.1016/s1570-0232(02)01010-3

Source DB:  PubMed          Journal:  J Chromatogr B Analyt Technol Biomed Life Sci        ISSN： 1570-0232            Impact factor:   3.205


  12 in total

1.  Plasma levels of B vitamins and colorectal cancer risk: the multiethnic cohort study.

Authors:  Loïc Le Marchand; Kami K White; Abraham M Y Nomura; Lynne R Wilkens; Jacob S Selhub; Maarit Tiirikainen; Marc T Goodman; Suzanne P Murphy; Brian E Henderson; Laurence N Kolonel
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2009-08       Impact factor: 4.254

2.  Sensitive and Stable Electrochemical Sensor for Folic Acid Determination Using a ZIF-67/AgNWs Nanocomposite.

Authors:  Yujiao Sun; Xue Wang; Hao Zhang
Journal:  Biosensors (Basel)       Date:  2022-05-31

Review 3.  Women Taking a Folic Acid Supplement in Countries with Mandatory Food Fortification Programs May Be Exceeding the Upper Tolerable Limit of Folic Acid: A Systematic Review.

Authors:  Carolyn Ledowsky; Abela Mahimbo; Vanessa Scarf; Amie Steel
Journal:  Nutrients       Date:  2022-06-29       Impact factor: 6.706

4.  Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop.

Authors:  Padma Maruvada; Patrick J Stover; Joel B Mason; Regan L Bailey; Cindy D Davis; Martha S Field; Richard H Finnell; Cutberto Garza; Ralph Green; Jean-Louis Gueant; Paul F Jacques; David M Klurfeld; Yvonne Lamers; Amanda J MacFarlane; Joshua W Miller; Anne M Molloy; Deborah L O'Connor; Christine M Pfeiffer; Nancy A Potischman; Joseph V Rodricks; Irwin H Rosenberg; Sharon A Ross; Barry Shane; Jacob Selhub; Sally P Stabler; Jacquetta Trasler; Sedigheh Yamini; Giovanna Zappalà
Journal:  Am J Clin Nutr       Date:  2020-11-11       Impact factor: 7.045

Review 5.  Biomarkers of Nutrition for Development-Folate Review.

Authors:  Lynn B Bailey; Patrick J Stover; Helene McNulty; Michael F Fenech; Jesse F Gregory; James L Mills; Christine M Pfeiffer; Zia Fazili; Mindy Zhang; Per M Ueland; Anne M Molloy; Marie A Caudill; Barry Shane; Robert J Berry; Regan L Bailey; Dorothy B Hausman; Ramkripa Raghavan; Daniel J Raiten
Journal:  J Nutr       Date:  2015-06-03       Impact factor: 4.798

6.  Lower risk of cervical intraepithelial neoplasia in women with high plasma folate and sufficient vitamin B12 in the post-folic acid fortification era.

Authors:  Chandrika J Piyathilake; Maurizio Macaluso; Ronald D Alvarez; Walter C Bell; Douglas C Heimburger; Edward E Partridge
Journal:  Cancer Prev Res (Phila)       Date:  2009-06-19

Review 7.  Folate, cancer risk, and the Greek god, Proteus: a tale of two chameleons.

Authors:  Joel B Mason
Journal:  Nutr Rev       Date:  2009-04       Impact factor: 7.110

8.  A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate.

Authors:  Renee D Kalmbach; Silvina F Choumenkovitch; Aron P Troen; Paul F Jacques; Ralph D'Agostino; Jacob Selhub
Journal:  J Nutr       Date:  2008-12       Impact factor: 4.798

9.  Circulating unmetabolized folic Acid: relationship to folate status and effect of supplementation.

Authors:  Carolyn Tam; Deborah O'Connor; Gideon Koren
Journal:  Obstet Gynecol Int       Date:  2012-02-19

10.  Folic acid fortification and public health: report on threshold doses above which unmetabolised folic acid appear in serum.

Authors:  Mary Rose Sweeney; Joseph McPartlin; John Scott
Journal:  BMC Public Health       Date:  2007-03-22       Impact factor: 3.295
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.