Literature DB >> 12665631

Proposal for a unified CCN nomenclature.

D R Brigstock1, R Goldschmeding, K-i Katsube, S C-T Lam, L F Lau, K Lyons, C Naus, B Perbal, B Riser, M Takigawa, H Yeger.   

Abstract

A proposal is put forth to unify the nomenclature of the CCN family of secreted, cysteine rich regulatory proteins. In the order of their description in the literature, CCN1 (CYR61), CCN2 (CTGF), CCN3 (NOV), CCN4 (WISP-1), CCN5 (WISP-2), and CCN6 (WISP-3) constitute a family of matricellular proteins that regulate cell adhesion, migration, proliferation, survival, and differentiation, at least in part through integrin mediated mechanisms. This proposal is endorsed by the International CCN Society and will serve to eliminate confusion from the multiple names that have been given to these molecules.

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Year:  2003        PMID: 12665631      PMCID: PMC1187305          DOI: 10.1136/mp.56.2.127

Source DB:  PubMed          Journal:  Mol Pathol        ISSN: 1366-8714


  9 in total

Review 1.  NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues.

Authors:  B Perbal
Journal:  Mol Pathol       Date:  2001-04

Review 2.  The CCN family of angiogenic regulators: the integrin connection.

Authors:  L F Lau; S C Lam
Journal:  Exp Cell Res       Date:  1999-04-10       Impact factor: 3.905

Review 3.  The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family.

Authors:  D R Brigstock
Journal:  Endocr Rev       Date:  1999-04       Impact factor: 19.871

4.  Report on the second international workshop on the CCN family of genes.

Authors:  B Perbal; D R Brigstock; L F Lau
Journal:  Mol Pathol       Date:  2003-04

Review 5.  The modular architecture of a new family of growth regulators related to connective tissue growth factor.

Authors:  P Bork
Journal:  FEBS Lett       Date:  1993-07-26       Impact factor: 4.124

6.  Expression of cyr61, a growth factor-inducible immediate-early gene.

Authors:  T P O'Brien; G P Yang; L Sanders; L F Lau
Journal:  Mol Cell Biol       Date:  1990-07       Impact factor: 4.272

7.  WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors.

Authors:  D Pennica; T A Swanson; J W Welsh; M A Roy; D A Lawrence; J Lee; J Brush; L A Taneyhill; B Deuel; M Lew; C Watanabe; R L Cohen; M F Melhem; G G Finley; P Quirke; A D Goddard; K J Hillan; A L Gurney; D Botstein; A J Levine
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

8.  Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas.

Authors:  V Joliot; C Martinerie; G Dambrine; G Plassiart; M Brisac; J Crochet; B Perbal
Journal:  Mol Cell Biol       Date:  1992-01       Impact factor: 4.272

9.  Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10.

Authors:  D M Bradham; A Igarashi; R L Potter; G R Grotendorst
Journal:  J Cell Biol       Date:  1991-09       Impact factor: 10.539

  9 in total
  93 in total

1.  Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice.

Authors:  Ernesto Canalis; Stefano Zanotti; Wesley G Beamer; Aris N Economides; Anna Smerdel-Ramoya
Journal:  Endocrinology       Date:  2010-06-09       Impact factor: 4.736

2.  CCN3 impairs osteoblast and stimulates osteoclast differentiation to favor breast cancer metastasis to bone.

Authors:  Véronique Ouellet; Kerstin Tiedemann; Anna Mourskaia; Jenna E Fong; Danh Tran-Thanh; Eitan Amir; Mark Clemons; Bernard Perbal; Svetlana V Komarova; Peter M Siegel
Journal:  Am J Pathol       Date:  2011-05       Impact factor: 4.307

Review 3.  The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis.

Authors:  John A Arnott; Alex G Lambi; Christina Mundy; Honey Hendesi; Robin A Pixley; Thomas A Owen; Fayez F Safadi; Steven N Popoff
Journal:  Crit Rev Eukaryot Gene Expr       Date:  2011       Impact factor: 1.807

Review 4.  The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis.

Authors:  Guo-Wei Zuo; Christopher D Kohls; Bai-Cheng He; Liang Chen; Wenli Zhang; Qiong Shi; Bing-Qiang Zhang; Quan Kang; Jinyong Luo; Xiaoji Luo; Eric R Wagner; Stephanie H Kim; Farbod Restegar; Rex C Haydon; Zhong-Liang Deng; Hue H Luu; Tong-Chuan He; Qing Luo
Journal:  Histol Histopathol       Date:  2010-06       Impact factor: 2.303

5.  New Approaches for Studying Alcoholic Liver Disease.

Authors:  Jun Xu; Xiao Liu; Bin Gao; Michael Karin; Hidekazu Tsukamoto; David Brenner; Tatiana Kisseleva
Journal:  Curr Pathobiol Rep       Date:  2014-09-14

Review 6.  Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localization.

Authors:  Andrew J Sawyer; Themis R Kyriakides
Journal:  Adv Drug Deliv Rev       Date:  2016-01-04       Impact factor: 15.470

7.  The official unified nomenclature adopted by the HGNC calls for the use of the acronyms, CCN1-6, and discontinuation in the use of CYR61, CTGF, NOV and WISP 1-3 respectively.

Authors:  Bernard Perbal; Susan Tweedie; Elspeth Bruford
Journal:  J Cell Commun Signal       Date:  2018-11-05       Impact factor: 5.782

Review 8.  Role of Age-Associated Alterations of the Dermal Extracellular Matrix Microenvironment in Human Skin Aging: A Mini-Review.

Authors:  Taihao Quan; Gary J Fisher
Journal:  Gerontology       Date:  2015-02-04       Impact factor: 5.140

9.  CCN2 as a novel molecule supporting energy metabolism of chondrocytes.

Authors:  Aya Maeda-Uematsu; Satoshi Kubota; Harumi Kawaki; Kazumi Kawata; Yoshiaki Miyake; Takako Hattori; Takashi Nishida; Norifumi Moritani; Karen M Lyons; Seiji Iida; Masaharu Takigawa
Journal:  J Cell Biochem       Date:  2014-05       Impact factor: 4.429

10.  CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells.

Authors:  Weike Si; Quan Kang; Hue H Luu; Jong Kyung Park; Qing Luo; Wen-Xin Song; Wei Jiang; Xiaoji Luo; Xinmin Li; Hong Yin; Anthony G Montag; Rex C Haydon; Tong-Chuan He
Journal:  Mol Cell Biol       Date:  2006-04       Impact factor: 4.272

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