Literature DB >> 30393824

The official unified nomenclature adopted by the HGNC calls for the use of the acronyms, CCN1-6, and discontinuation in the use of CYR61, CTGF, NOV and WISP 1-3 respectively.

Bernard Perbal1, Susan Tweedie2, Elspeth Bruford2.   

Abstract

An examination of the confusion generated around the use of different acronyms for CCN proteins has been performed by the editors of the HUGO Gene Nomenclature Committee upon the request of the International CCN Society Scientific Committee. After careful consideration of the various arguments, and after polling the community of researchers who have published in the field over the past ten years, the HGNC have decided to adopt and approve the CCN nomenclature for all 6 genes. Effective October 2018, the genes referred to as CYR61, CTGF, NOV and WISP1-3 will be respectively designated by the gene symbols CCN1-6 with corresponding gene names « cellular communication Q2 network factor 1-6 ». We believe that this decision will be a step towards better communication between researchers working in the field, and will set the stage for fruitful collaborative projects. Accordingly, the Journal of Cell Communication and Signaling, the official journal of the International CCN Society, available both in print and online, constitutes a unique window into the CCN field. This official nomenclature will benefit the international scientific community that is supported by the established and renowned professionalism of the Springer-Nature publishing group.

Entities:  

Keywords:  CCN proteins; CCNgenes; CTGF; CYR61; Cellular communication network factor; NOV; WISP1; WISP2; WISP3

Year:  2018        PMID: 30393824      PMCID: PMC6235780          DOI: 10.1007/s12079-018-0491-1

Source DB:  PubMed          Journal:  J Cell Commun Signal        ISSN: 1873-9601            Impact factor:   5.782


  15 in total

Review 1.  NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues.

Authors:  B Perbal
Journal:  Mol Pathol       Date:  2001-04

2.  CCN3 is a novel endogenous PDGF-regulated inhibitor of glomerular cell proliferation.

Authors:  C R C van Roeyen; F Eitner; T Scholl; P Boor; U Kunter; N Planque; H-J Gröne; A M Bleau; B Perbal; T Ostendorf; J Floege
Journal:  Kidney Int       Date:  2007-10-10       Impact factor: 10.612

Review 3.  The modular architecture of a new family of growth regulators related to connective tissue growth factor.

Authors:  P Bork
Journal:  FEBS Lett       Date:  1993-07-26       Impact factor: 4.124

4.  The CCN family of proteins: a 25th anniversary picture.

Authors:  Annick Perbal; Bernard Perbal
Journal:  J Cell Commun Signal       Date:  2016-08-31       Impact factor: 5.782

Review 5.  The concept of the CCN protein family revisited: a centralized coordination network.

Authors:  Bernard Perbal
Journal:  J Cell Commun Signal       Date:  2018-02-22       Impact factor: 5.782

6.  WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene.

Authors:  L Xu; R B Corcoran; J W Welsh; D Pennica; A J Levine
Journal:  Genes Dev       Date:  2000-03-01       Impact factor: 11.361

7.  CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease.

Authors:  Bruce L Riser; Feridoon Najmabadi; Bernard Perbal; Darryl R Peterson; Jo Ann Rambow; Melisa L Riser; Ernest Sukowski; Herman Yeger; Sarah C Riser
Journal:  Am J Pathol       Date:  2009-04-09       Impact factor: 4.307

8.  WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors.

Authors:  D Pennica; T A Swanson; J W Welsh; M A Roy; D A Lawrence; J Lee; J Brush; L A Taneyhill; B Deuel; M Lew; C Watanabe; R L Cohen; M F Melhem; G G Finley; P Quirke; A D Goddard; K J Hillan; A L Gurney; D Botstein; A J Levine
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

Review 9.  CCN proteins: multifunctional signalling regulators.

Authors:  Bernard Perbal
Journal:  Lancet       Date:  2004-01-03       Impact factor: 79.321

Review 10.  Contribution of MAV-1-induced nephroblastoma to the study of genes involved in human Wilms' tumor development.

Authors:  B Perbal
Journal:  Crit Rev Oncog       Date:  1994
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  33 in total

1.  2021: a new turn for JCCS.

Authors:  Bernard Perbal
Journal:  J Cell Commun Signal       Date:  2021-02-04       Impact factor: 5.782

2.  Editorial.

Authors:  Bernard Perbal
Journal:  J Cell Commun Signal       Date:  2019-03       Impact factor: 5.782

3.  Ependyma-expressed CCN1 restricts the size of the neural stem cell pool in the adult ventricular-subventricular zone.

Authors:  Jun Wu; Wen-Jia Tian; Yang Liu; Huanhuan J Wang; Jiangli Zheng; Xin Wang; Han Pan; Ji Li; Junyu Luo; Xuerui Yang; Lester F Lau; H Troy Ghashghaei; Qin Shen
Journal:  EMBO J       Date:  2020-02-03       Impact factor: 11.598

4.  What a long, strange trip it's been.

Authors:  Andrew Leask
Journal:  J Cell Commun Signal       Date:  2020-03       Impact factor: 5.782

Review 5.  Conjunction junction, what's the function? CCN proteins as targets in fibrosis and cancers.

Authors:  Andrew Leask
Journal:  Am J Physiol Cell Physiol       Date:  2020-03-04       Impact factor: 4.249

6.  WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial-mesenchymal transition.

Authors:  Wentao Deng; Audry Fernandez; Sarah L McLaughlin; David J Klinke
Journal:  J Biol Chem       Date:  2019-02-05       Impact factor: 5.157

Review 7.  Caught between a "Rho" and a hard place: are CCN1/CYR61 and CCN2/CTGF the arbiters of microvascular stiffness?

Authors:  Brahim Chaqour
Journal:  J Cell Commun Signal       Date:  2019-08-02       Impact factor: 5.782

Review 8.  Drugs in phase I and phase II clinical trials for systemic sclerosis.

Authors:  Melody P Chung; Lorinda Chung
Journal:  Expert Opin Investig Drugs       Date:  2020-03-25       Impact factor: 6.206

Review 9.  CTGF/CCN2 from Skeletal Muscle to Nervous System: Impact on Neurodegenerative Diseases.

Authors:  David Gonzalez; Enrique Brandan
Journal:  Mol Neurobiol       Date:  2019-01-28       Impact factor: 5.590

Review 10.  Cellular communication network factor 3 in cartilage development and maintenance.

Authors:  Satoshi Kubota; Harumi Kawaki; Bernard Perbal; Kazumi Kawata; Takako Hattori; Takashi Nishida
Journal:  J Cell Commun Signal       Date:  2021-06-14       Impact factor: 5.782

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