Literature DB >> 12660931

Association between chronic disseminated candidiasis in adult acute leukemia and common IL4 promoter haplotypes.

Eun Hwa Choi1, Charles B Foster, James G Taylor, Hans Christian Erichsen, Renee A Chen, Thomas J Walsh, Veli-Jukka Anttila, Tapani Ruutu, Aarno Palotie, Stephen J Chanock.   

Abstract

Chronic disseminated candidiasis (CDC) is a form of Candida species infection observed primarily in patients with acute leukemia. To investigate possible genetic factors associated with CDC, we conducted a pilot study of 40 patients with both leukemia and CDC and 50 control patients with leukemia only. A common haplotype of the IL4 promoter (-1098T/-589C/-33C) was overrepresented in patients with CDC (P= .01; odds ratio [OR], 2.16), whereas another common haplotype (-1098T/-589T/-33T) appeared to be protective against CDC (P= .018; OR, 0.47). Genetic variants of IL4 could contribute to the development of CDC in patients with acute leukemia.

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Year:  2003        PMID： 12660931     DOI： 10.1086/368345

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  16 in total

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2.  Genotype frequency and F ST analysis of polymorphisms in immunoregulatory genes in Chinese and Caucasian populations.

Authors:  Qing Lan; Min Shen; Dino Garcia-Rossi; Stephen Chanock; Tongzhang Zheng; Sonja I Berndt; Vinita Puri; Guilan Li; Xingzhou He; Robert Welch; Shelia H Zahm; Luoping Zhang; Yawei Zhang; Martyn Smith; Sophia S Wang; Brian C-H Chiu; Martha Linet; Richard Hayes; Nathaniel Rothman; Meredith Yeager
Journal:  Immunogenetics       Date:  2007-10-16       Impact factor: 2.846

Review 3.  Host genetics of invasive Aspergillus and Candida infections.

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Journal:  Semin Immunopathol       Date:  2014-11-18       Impact factor: 9.623

4.  Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma.

Authors:  Qing Lan; Tongzhang Zheng; Nathaniel Rothman; Yawei Zhang; Sophia S Wang; Min Shen; Sonja I Berndt; Shelia H Zahm; Theodore R Holford; Brian Leaderer; Meredith Yeager; Robert Welch; Peter Boyle; Bing Zhang; Kaiyong Zou; Yong Zhu; Stephen Chanock
Journal:  Blood       Date:  2006-01-31       Impact factor: 22.113

Review 5.  Immunity to fungal infections.

Authors:  Luigina Romani
Journal:  Nat Rev Immunol       Date:  2011-03-11       Impact factor: 53.106

6.  Genetic Susceptibility to Fungal Infections: What is in the Genes?

Authors:  Stacey A Maskarinec; Melissa D Johnson; John R Perfect
Journal:  Curr Clin Microbiol Rep       Date:  2016-03-29

7.  Polymorphisms in Host Immunity-Modulating Genes and Risk of Invasive Aspergillosis: Results from the AspBIOmics Consortium.

Authors:  C B Lupiañez; L M Canet; A Carvalho; L Alcazar-Fuoli; J Springer; M Lackner; J Segura-Catena; A Comino; C Olmedo; R Ríos; A Fernández-Montoya; M Cuenca-Estrella; C Solano; M Á López-Nevot; C Cunha; A Oliveira-Coelho; T Villaescusa; L Fianchi; J M Aguado; L Pagano; E López-Fernández; L Potenza; M Luppi; C Lass-Flörl; J Loeffler; H Einsele; L Vazquez; M Jurado; J Sainz
Journal:  Infect Immun       Date:  2015-12-14       Impact factor: 3.441

Review 8.  Genetic susceptibility to Candida infections.

Authors:  Sanne P Smeekens; Frank L van de Veerdonk; Bart Jan Kullberg; Mihai G Netea
Journal:  EMBO Mol Med       Date:  2013-04-30       Impact factor: 12.137

Review 9.  Research priorities for neglected infectious diseases in Latin America and the Caribbean region.

Authors:  Jean-Claude Dujardin; Socrates Herrera; Virgilio do Rosario; Jorge Arevalo; Marleen Boelaert; Hernan J Carrasco; Rodrigo Correa-Oliveira; Lineth Garcia; Eduardo Gotuzzo; Theresa W Gyorkos; Alexis M Kalergis; Gustavo Kouri; Vicente Larraga; Pascal Lutumba; Maria Angeles Macias Garcia; Pablo C Manrique-Saide; Farrokh Modabber; Alberto Nieto; Gerd Pluschke; Carlos Robello; Antonieta Rojas de Arias; Martin Rumbo; Jose Ignacio Santos Preciado; Shyam Sundar; Jaime Torres; Faustino Torrico; Patrick Van der Stuyft; Kathleen Victoir; Ole F Olesen
Journal:  PLoS Negl Trop Dis       Date:  2010-10-26

Review 10.  SNPs in cancer research and treatment.

Authors:  H C Erichsen; S J Chanock
Journal:  Br J Cancer       Date:  2004-02-23       Impact factor: 7.640
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