Literature DB >> 12656607

Kinetics of unfolding the human telomeric DNA quadruplex using a PNA trap.

Jeremy J Green1, Liming Ying, David Klenerman, Shankar Balasubramanian.   

Abstract

The kinetics of opening of the DNA quadruplex formed by the human telomeric repeat have been investigated using real-time fluorescence resonance energy transfer (FRET) measurements with a peptide nucleic acid (PNA) trap. It has been found that this opening is zero-order with respect to PNA, indicating that the initial step is a rate-limiting internal rearrangement of the quadruplex. A study of the temperature dependence of the rate of quadruplex opening was performed and the activation energy of the process estimated to be 98 +/- 8 kJ mol(-1).

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Year:  2003        PMID： 12656607     DOI： 10.1021/ja029149w

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  39 in total

1.  The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element.

Authors:  Susanna Cogoi; Manikandan Paramasivam; Alexandro Membrino; Kazunari K Yokoyama; Luigi E Xodo
Journal:  J Biol Chem       Date:  2010-05-10       Impact factor: 5.157

2.  Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer.

Authors:  Liming Ying; Jeremy J Green; Haitao Li; David Klenerman; Shankar Balasubramanian
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-25       Impact factor: 11.205

3.  Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics.

Authors:  Anh Tuân Phan; Dinshaw J Patel
Journal:  J Am Chem Soc       Date:  2003-12-10       Impact factor: 15.419

Review 4.  DNA architecture: from G to Z.

Authors:  Anh Tuân Phan; Vitaly Kuryavyi; Dinshaw J Patel
Journal:  Curr Opin Struct Biol       Date:  2006-05-22       Impact factor: 6.809

5.  Folding Landscape of a Parallel G-Quadruplex.

Authors:  Robert D Gray; John O Trent; Sengodagounder Arumugam; Jonathan B Chaires
Journal:  J Phys Chem Lett       Date:  2019-02-27       Impact factor: 6.475

6.  Hybridization of complementary and homologous peptide nucleic acid oligomers to a guanine quadruplex-forming RNA.

Authors:  Violeta L Marin; Bruce A Armitage
Journal:  Biochemistry       Date:  2006-02-14       Impact factor: 3.162

7.  Noncovalent binding and fluorogenic response of cyanine dyes to DNA homoquadruplex and PNA-DNA heteroquadruplex structures.

Authors:  Halimatu S Mohammed; Junriz O Delos Santos; Bruce A Armitage
Journal:  Artif DNA PNA XNA       Date:  2011-04

8.  Homologous PNA Hybridization to Noncanonical DNA G-Quadruplexes.

Authors:  Karen A Kormuth; John L Woolford; Bruce A Armitage
Journal:  Biochemistry       Date:  2016-03-16       Impact factor: 3.162

9.  Single molecule force spectroscopy on G-quadruplex DNA.

Authors:  Susanna Lynch; Heather Baker; Sarah G Byker; Dejian Zhou; Kumar Sinniah
Journal:  Chemistry       Date:  2009-08-17       Impact factor: 5.236

10.  Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs.

Authors:  Mykola I Onyshchenko; Timur I Gaynutdinov; Ethan A Englund; Daniel H Appella; Ronald D Neumann; Igor G Panyutin
Journal:  Nucleic Acids Res       Date:  2009-12       Impact factor: 16.971
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