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Literature DB >> 12654685

Novel tetracycline resistance determinant from the oral metagenome.

M L Diaz-Torres¹, R McNab, D A Spratt, A Villedieu, N Hunt, M Wilson, P Mullany.

Abstract

A major drawback of most studies on how bacteria become resistant to antibiotics is that they concentrate mainly on bacteria that can be cultivated in the laboratory. In the present study, we cloned part of the oral metagenome and isolated a novel tetracycline resistance gene, tet(37), which inactivates tetracycline.

Entities: Chemical Species

Mesh：

Year: 2003 PMID： 12654685 PMCID： PMC152525 DOI： 10.1128/AAC.47.4.1430-1432.2003

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

5 in total

1. Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon.

Authors: N B Shoemaker; H Vlamakis; K Hayes; A A Salyers
Journal: Appl Environ Microbiol Date: 2001-02 Impact factor: 4.792

2. Molecular ecology of tetracycline resistance: development and validation of primers for detection of tetracycline resistance genes encoding ribosomal protection proteins.

Authors: R I Aminov; N Garrigues-Jeanjean; R I Mackie
Journal: Appl Environ Microbiol Date: 2001-01 Impact factor: 4.792

3. Evidence that a novel tetracycline resistance gene found on two Bacteroides transposons encodes an NADP-requiring oxidoreductase.

Authors: B S Speer; L Bedzyk; A A Salyers
Journal: J Bacteriol Date: 1991-01 Impact factor: 3.490

4. Diversity of oral asaccharolytic Eubacterium species in periodontitis--identification of novel phylotypes representing uncultivated taxa.

Authors: D A Spratt; A J Weightman; W G Wade
Journal: Oral Microbiol Immunol Date: 1999-02

Review 5. Unculturable bacteria--the uncharacterized organisms that cause oral infections.

Authors: William Wade
Journal: J R Soc Med Date: 2002-02 Impact factor: 18.000

5 in total

30 in total

1. Cloning, expression and characterization of a metagenome derived thermoactive/thermostable pectinase.

Authors: Rajvinder Singh; Samriti Dhawan; Kashmir Singh; Jagdeep Kaur
Journal: Mol Biol Rep Date: 2012-06-19 Impact factor: 2.316

Review 2. Metagenomics: application of genomics to uncultured microorganisms.

Authors: Jo Handelsman
Journal: Microbiol Mol Biol Rev Date: 2004-12 Impact factor: 11.056

3. Development of high-throughput phenotyping of metagenomic clones from the human gut microbiome for modulation of eukaryotic cell growth.

Authors: Karine Gloux; Marion Leclerc; Harout Iliozer; René L'Haridon; Chaysavanh Manichanh; Gérard Corthier; Renaud Nalin; Hervé M Blottière; Joël Doré
Journal: Appl Environ Microbiol Date: 2007-03-30 Impact factor: 4.792

Review 4. The tetracycline resistome.

Authors: Maulik Thaker; Peter Spanogiannopoulos; Gerard D Wright
Journal: Cell Mol Life Sci Date: 2009-10-28 Impact factor: 9.261

Novel tetracycline resistance determinant from the oral metagenome.

1. Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon.

2. Molecular ecology of tetracycline resistance: development and validation of primers for detection of tetracycline resistance genes encoding ribosomal protection proteins.

3. Evidence that a novel tetracycline resistance gene found on two Bacteroides transposons encodes an NADP-requiring oxidoreductase.

4. Diversity of oral asaccharolytic Eubacterium species in periodontitis--identification of novel phylotypes representing uncultivated taxa.

Review 5. Unculturable bacteria--the uncharacterized organisms that cause oral infections.

1. Cloning, expression and characterization of a metagenome derived thermoactive/thermostable pectinase.

Review 2. Metagenomics: application of genomics to uncultured microorganisms.

3. Development of high-throughput phenotyping of metagenomic clones from the human gut microbiome for modulation of eukaryotic cell growth.

Review 4. The tetracycline resistome.

5. Characterization of antibiotic resistance determinants in oral biofilms.

6. Insights into resistome and stress responses genes in Bubalus bubalis rumen through metagenomic analysis.

7. Metagenomics in animal gastrointestinal ecosystem: a microbiological and biotechnological perspective.

8. Improved annotation of antibiotic resistance determinants reveals microbial resistomes cluster by ecology.

Review 9. Prokaryotic and eukaryotic diversity in hydrothermal continental systems.

Review 10. Tetracycline Antibiotics and Resistance.