Literature DB >> 12652179

Atrial fibrillation ablation leads to long-term improvement of quality of life and reduced utilization of healthcare resources.

Andrea Goldberg1, Michael Menen, Steven Mickelsen, Chamisa MacIndoe, Mario Binder, Rosella Nawman, Gail West, Fred M Kusumoto.   

Abstract

In some patients, rapid activation from one or several foci can lead to atrial fibrillation. This study evaluated long-term changes in quality of life and healthcare resource utilization in patients with atrial fibrillation treated by ablation of focal triggers. Thirty-three patients underwent ablation for paroxysmal atrial fibrillation. Health surveys (SF-36) were obtained at baseline, and after 1 year and 3 years of follow-up. Health care costs were measured for the 3 years before and after ablation. Ablation was successful in 82%, partially successful in 12% (no sustained episodes but on antiarrhythmic drug therapy), and unsuccessful in 6% of patients. The average number of ablation procedures was 1.6 +/- 0.6 per patient. After ablation, patients reported significantly improved quality of life in all SF-36 categories except bodily pain. Healthcare resource utilization was significantly reduced after ablation (Clinic visits: 7.4 +/- 2.5 per year vs. 1.1 +/- 0.6 per year, p < 0.05; Emergency room visits: 1.7 +/- 0.90 per year vs. 0.03 +/- 0.17 per year, p < 0.05; Hospitalization: 1.6 +/- 0.81 vs. 0, p < 0.05). Cost of healthcare (not including procedural costs) was significantly reduced after ablation (Pre-ablation: 1,920 +/- 889 dollars/year vs. post-ablation: 87 +/- 68 dollars/year; p < 0.01). Procedural cost of ablation was 17,173 +/- 2,466 dollars/patient. Ablation of focal triggers of atrial fibrillation is associated with a sustained improvement in quality of life. Although the initial cost of ablation is high, after ablation, utilization of healthcare resources is significantly reduced.

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Year:  2003        PMID: 12652179     DOI: 10.1023/a:1022348216072

Source DB:  PubMed          Journal:  J Interv Card Electrophysiol        ISSN: 1383-875X            Impact factor:   1.900


  12 in total

1.  The impairment of health-related quality of life in patients with intermittent atrial fibrillation: implications for the assessment of investigational therapy.

Authors:  P Dorian; W Jung; D Newman; M Paquette; K Wood; G M Ayers; J Camm; M Akhtar; B Luderitz
Journal:  J Am Coll Cardiol       Date:  2000-10       Impact factor: 24.094

2.  The MOS short-form general health survey. Reliability and validity in a patient population.

Authors:  A L Stewart; R D Hays; J E Ware
Journal:  Med Care       Date:  1988-07       Impact factor: 2.983

3.  Quality of life and outcomes after radiofrequency His-bundle catheter ablation and permanent pacemaker implantation: impact of treatment in paroxysmal and established atrial fibrillation.

Authors:  A P Fitzpatrick; H D Kourouyan; A Siu; R J Lee; M D Lesh; L M Epstein; J C Griffin; M M Scheinman
Journal:  Am Heart J       Date:  1996-03       Impact factor: 4.749

4.  Radiofrequency catheter ablation versus medical therapy for initial treatment of supraventricular tachycardia and its impact on quality of life and healthcare costs.

Authors:  M N Bathina; S Mickelsen; C Brooks; J Jaramillo; T Hepton; F M Kusumoto
Journal:  Am J Cardiol       Date:  1998-09-01       Impact factor: 2.778

5.  Clinical outcome after radiofrequency catheter ablation of focal atrial fibrillation triggers.

Authors:  E P Gerstenfeld; P Guerra; P B Sparks; K Hattori; M D Lesh
Journal:  J Cardiovasc Electrophysiol       Date:  2001-08

6.  Assessment of atrioventricular junction ablation and DDDR mode-switching pacemaker versus pharmacological treatment in patients with severely symptomatic paroxysmal atrial fibrillation: a randomized controlled study.

Authors:  M Brignole; L Gianfranchi; C Menozzi; P Alboni; G Musso; M G Bongiorni; M Gasparini; A Raviele; G Lolli; N Paparella; S Acquarone
Journal:  Circulation       Date:  1997-10-21       Impact factor: 29.690

7.  A focal source of atrial fibrillation treated by discrete radiofrequency ablation.

Authors:  P Jaïs; M Haïssaguerre; D C Shah; S Chouairi; L Gencel; M Hocini; J Clémenty
Journal:  Circulation       Date:  1997-02-04       Impact factor: 29.690

8.  Pulmonary vein isolation for paroxysmal and persistent atrial fibrillation.

Authors:  Hakan Oral; Bradley P Knight; Hiroshi Tada; Mehmet Ozaydin; Aman Chugh; Sohail Hassan; Christoph Scharf; Steve W K Lai; Radmira Greenstein; Frank Pelosi; S Adam Strickberger; Fred Morady
Journal:  Circulation       Date:  2002-03-05       Impact factor: 29.690

9.  Effect of radiofrequency catheter ablation on health-related quality of life and activities of daily living in patients with recurrent arrhythmias.

Authors:  R S Bubien; S M Knotts-Dolson; V J Plumb; G N Kay
Journal:  Circulation       Date:  1996-10-01       Impact factor: 29.690

10.  Cost-effectiveness of radiofrequency ablation compared with other strategies in Wolff-Parkinson-White syndrome.

Authors:  W Hogenhuis; S K Stevens; P Wang; J B Wong; A S Manolis; N A Estes; S G Pauker
Journal:  Circulation       Date:  1993-11       Impact factor: 29.690

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  13 in total

Review 1.  2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design.

Authors:  Hugh Calkins; Karl Heinz Kuck; Riccardo Cappato; Josep Brugada; A John Camm; Shih-Ann Chen; Harry J G Crijns; Ralph J Damiano; D Wyn Davies; John DiMarco; James Edgerton; Kenneth Ellenbogen; Michael D Ezekowitz; David E Haines; Michel Haissaguerre; Gerhard Hindricks; Yoshito Iesaka; Warren Jackman; Jose Jalife; Pierre Jais; Jonathan Kalman; David Keane; Young-Hoon Kim; Paulus Kirchhof; George Klein; Hans Kottkamp; Koichiro Kumagai; Bruce D Lindsay; Moussa Mansour; Francis E Marchlinski; Patrick M McCarthy; J Lluis Mont; Fred Morady; Koonlawee Nademanee; Hiroshi Nakagawa; Andrea Natale; Stanley Nattel; Douglas L Packer; Carlo Pappone; Eric Prystowsky; Antonio Raviele; Vivek Reddy; Jeremy N Ruskin; Richard J Shemin; Hsuan-Ming Tsao; David Wilber
Journal:  J Interv Card Electrophysiol       Date:  2012-03       Impact factor: 1.900

Review 2.  The Impact of Atrial Fibrillation Ablation on Quality of Life.

Authors:  Jacob Pontoppidan
Journal:  J Atr Fibrillation       Date:  2012-10-06

Review 3.  The state of patient-reported outcomes in atrial fibrillation : a review of current measures.

Authors:  Karin Coyne; Mary Kay Margolis; Susan Grandy; Peter Zimetbaum
Journal:  Pharmacoeconomics       Date:  2005       Impact factor: 4.981

4.  Survey of physician experience, trends and outcomes with atrial fibrillation ablation.

Authors:  Steven Mickelsen; Ben Dudley; Eric Treat; John Barela; John Omdahl; Fred Kusumoto
Journal:  J Interv Card Electrophysiol       Date:  2005-04       Impact factor: 1.900

5.  Safety and efficacy of catheter ablation of atrial fibrillation in patients with diabetes mellitus--single center experience.

Authors:  Ri Bo Tang; Jian Zeng Dong; Xing Peng Liu; Dong Ping Fang; De Yong Long; Xiao Hui Liu; Rong Hui Yu; Fu Li Hu; Chun Shan Lu; Peng Hao; Jérôme Kalifa; Chang Sheng Ma
Journal:  J Interv Card Electrophysiol       Date:  2007-01-18       Impact factor: 1.900

Review 6.  The transition to value-based care.

Authors:  Jordan C Ray; Fred Kusumoto
Journal:  J Interv Card Electrophysiol       Date:  2016-07-21       Impact factor: 1.900

7.  Healthcare resource utilization and costs associated with recurrent episodes of atrial fibrillation: the FRACTAL registry.

Authors:  Matthew R Reynolds; Vidal Essebag; Peter Zimetbaum; David J Cohen
Journal:  J Cardiovasc Electrophysiol       Date:  2007-04-19

8.  Cost-effectiveness of radiofrequency catheter ablation compared with antiarrhythmic drug therapy for paroxysmal atrial fibrillation.

Authors:  Matthew R Reynolds; Peter Zimetbaum; Mark E Josephson; Ethan Ellis; Tatyana Danilov; David J Cohen
Journal:  Circ Arrhythm Electrophysiol       Date:  2009-04-17

9.  Evaluating the Cost-effectiveness of Catheter Ablation of Atrial Fibrillation.

Authors:  Andrew Y Chang; Daniel Kaiser; Aditya Ullal; Alexander C Perino; Paul A Heidenreich; Mintu P Turakhia
Journal:  Arrhythm Electrophysiol Rev       Date:  2014-11-29

Review 10.  Quality of life in atrial fibrillation: measurement tools and impact of interventions.

Authors:  Matthew R Reynolds; Ethan Ellis; Peter Zimetbaum
Journal:  J Cardiovasc Electrophysiol       Date:  2008-02-05
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