Literature DB >> 12648255

Host-environment medicine: a primary care model for the age of genomics.

Peter M Rabinowitz1, Alex Poljak.   

Abstract

Rapid developments in genomic and proteomic testing promise to impact the way in which clinicians assess disease risk and drug selection in their patients. Because most diseases result from host-environment interactions, however, primary care providers will need to avoid the trap of biological determinism by examining the important role of environmental factors in their clinical assessments and interventions. This article discusses the application of host-environment concepts to recent developments in the areas of genomics and proteomics.

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Year:  2003        PMID: 12648255      PMCID: PMC1494830          DOI: 10.1046/j.1525-1497.2003.11101.x

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  38 in total

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5.  Use of proteomic patterns in serum to identify ovarian cancer.

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7.  The effect of tobacco on lung cancer risk depends on CYP2D6 activity.

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8.  Risk of smoking for squamous and small cell carcinomas of the lung modulated by combinations of CYP1A1 and GSTM1 gene polymorphisms in a Japanese population.

Authors:  M Kihara; M Kihara; K Noda
Journal:  Carcinogenesis       Date:  1995-10       Impact factor: 4.944

9.  Patient-tailored antiemetic treatment with 5-hydroxytryptamine type 3 receptor antagonists according to cytochrome P-450 2D6 genotypes.

Authors:  Rolf Kaiser; Orhan Sezer; Anja Papies; Steffen Bauer; Claudia Schelenz; Pierre-Benoit Tremblay; Kurt Possinger; Ivar Roots; Jürgen Brockmöller
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10.  Hypotheses to explain the higher symptom rates observed around hazardous waste sites.

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Journal:  Environ Health Perspect       Date:  1991-08       Impact factor: 9.031

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Review 2.  From "us vs. them" to "shared risk": can animals help link environmental factors to human health?

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3.  Systems biology: new approaches to old environmental health problems.

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  3 in total

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