UNLABELLED: A 10-year-old girl presented left ventricular failure 1 month after the onset of hemolytic uremic syndrome (HUS) caused by an Escherichia coli O157 infection and was diagnosed as having dilated cardiomyopathy. Thallium myocardial scintigraphy showed normal perfusion, but no myocardial uptake of iodine-123-( R, S)-15-( p-iodophenyl)-3-methylpentadecanoic acid ((123)I-BMIPP) was observed. We analyzed the CD36 expression in platelets and monocytes by using a flowcytometer, and she turned out to have CD36 deficiency type I. CONCLUSION: Some patients may be predisposed to myocardial damage in the presence of CD36 deficiency. It is necessary to clarify the etiological significance of the relationship between cardiac impairment and CD36 deficiency in children.
UNLABELLED: A 10-year-old girl presented left ventricular failure 1 month after the onset of hemolytic uremic syndrome (HUS) caused by an Escherichia coli O157 infection and was diagnosed as having dilated cardiomyopathy. Thallium myocardial scintigraphy showed normal perfusion, but no myocardial uptake of iodine-123-( R, S)-15-( p-iodophenyl)-3-methylpentadecanoic acid ((123)I-BMIPP) was observed. We analyzed the CD36 expression in platelets and monocytes by using a flowcytometer, and she turned out to have CD36 deficiency type I. CONCLUSION: Some patients may be predisposed to myocardial damage in the presence of CD36 deficiency. It is necessary to clarify the etiological significance of the relationship between cardiac impairment and CD36 deficiency in children.
Authors: T Yoshizumi; S Nozaki; K Fukuchi; K Yamasaki; T Fukuchi; T Maruyama; Y Tomiyama; S Yamashita; T Nishimura; Y Matsuzawa Journal: J Nucl Med Date: 2000-07 Impact factor: 10.057
Authors: H Yanai; H Chiba; H Fujiwara; M Morimoto; K Abe; S Yoshida; Y Takahashi; H Fuda; S P Hui; H Akita; K Kobayashi; K Matsuno Journal: Thromb Haemost Date: 2000-09 Impact factor: 5.249
Authors: C Kurata; K Tawarahara; T Taguchi; S Aoshima; A Kobayashi; N Yamazaki; H Kawai; M Kaneko Journal: J Nucl Med Date: 1992-01 Impact factor: 10.057