Literature DB >> 12628664

Synthesis and in vitro leishmanicidal activity of some hydrazides and their analogues.

Khalid Mohammad Khan1, Maimona Rasheed, Safdar Hayat, Farhana Kaukab, M Iqbal Choudhary, Shahnaz Perveen.   

Abstract

Twenty-one hydrazides were synthesized by treating different esters with hydrazine hydrate. Substituted hydrazides were obtained by treating hydrazides with alkyl/aryl/acyl halides. Some of these compounds exhibit potential in vitro leishmanicidal activity. The structures of all the synthesized compounds were confirmed by spectroscopic analysis.

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Year:  2003        PMID： 12628664     DOI： 10.1016/s0968-0896(02)00611-9

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  3 in total

1.  Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement.

Authors:  Mohamed O Radwan; Halil I Ciftci; Taha F S Ali; Doha E Ellakwa; Ryoko Koga; Hiroshi Tateishi; Akiko Nakata; Akihiro Ito; Minoru Yoshida; Yoshinari Okamoto; Mikako Fujita; Masami Otsuka
Journal:  Molecules       Date:  2019-09-10       Impact factor: 4.411

2.  The Synthesis and Anion Recognition Property of Symmetrical Chemosensors Involving Thiourea Groups: Theory and Experiments.

Authors:  Xuefang Shang; Zhenhua Yang; Jiajia Fu; Peipei Zhao; Xiufang Xu
Journal:  Sensors (Basel)       Date:  2015-11-06       Impact factor: 3.576

3.  Synthesis and Structure Insights of Two Novel Broad-Spectrum Antibacterial Candidates Based on (E)-N'-[(Heteroaryl)methylene]adamantane-1-carbohydrazides.

Authors:  Lamya H Al-Wahaibi; Natalia Alvarez; Olivier Blacque; Nicolás Veiga; Aamal A Al-Mutairi; Ali A El-Emam
Journal:  Molecules       Date:  2020-04-22       Impact factor: 4.411
  3 in total

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