Literature DB >> 12628397

Quantitative HPLC analysis of withanolides in Withania somnifera.

M Ganzera1, M I Choudhary, I A Khan.   

Abstract

One of the most widely used herbs in Ayurvedic medicine is Ashwaghanda, Withania somnifera, a shrub commonly found on the Indian subcontinent. As this plant is increasingly becoming a popular adaptogenic in the western world, analytical methods for its identification and quality control are in demand. Thus, a HPLC method for the determination of withaferin A and withanolide D was developed. The system was successfully used to investigate the presence of the markers in different W. somnifera plant parts as well as to analyze their content in market products.

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Year:  2003        PMID： 12628397     DOI： 10.1016/s0367-326x(02)00325-8

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  15 in total

1.  Neuroprotective effects of Withania somnifera dunal.: A possible mechanism.

Authors:  Maheep Bhatnagar; Durgesh Sharma; Mahendra Salvi
Journal:  Neurochem Res       Date:  2009-05-15       Impact factor: 3.996

2.  Comparing the cytotoxic potential of Withania somnifera water and methanol extracts.

Authors:  Etheresia Pretorius; Hester Magdalena Oberholzer; Petrus Johannes Becker
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-05-07

3.  Ectopic overexpression of WsSGTL1, a sterol glucosyltransferase gene in Withania somnifera, promotes growth, enhances glycowithanolide and provides tolerance to abiotic and biotic stresses.

Authors:  Syed Saema; Laiq Ur Rahman; Ruchi Singh; Abhishek Niranjan; Iffat Zareen Ahmad; Pratibha Misra
Journal:  Plant Cell Rep       Date:  2015-10-30       Impact factor: 4.570

4.  Small molecule anti-angiogenic probes of the ubiquitin proteasome pathway: potential application to choroidal neovascularization.

Authors:  Paola Bargagna-Mohan; Padma Priya Ravindranath; Royce Mohan
Journal:  Invest Ophthalmol Vis Sci       Date:  2006-09       Impact factor: 4.799

5.  Foliar application of elicitors enhanced the yield of withanolide contents in Withania somnifera (L.) Dunal (variety, Poshita).

Authors:  Manali Singh; Nitesh Kumar Poddar; Dipti Singh; Sanjeev Agrawal
Journal:  3 Biotech       Date:  2020-03-04       Impact factor: 2.406

6.  Gastroprotective effect of standardized extract of Amukkara choornam on experimental gastric ulcer in rats.

Authors:  Kartik Chandra Patra; K Jayaram Kumar; Dheeraj Kumar Ahirwar
Journal:  J Nat Med       Date:  2013-08-11       Impact factor: 2.343

7.  Standardization of a Siddha formulation Amukkara curanam by HPTLC.

Authors:  N S Jeganathan; K Kannan; R Manavalan; Hannah R Vasanthi
Journal:  Afr J Tradit Complement Altern Med       Date:  2008-01-22

8.  Roots of Withania somnifera Inhibit Forestomach and Skin Carcinogenesis in Mice.

Authors:  Bandhuvula Padmavathi; Pramod C Rath; Araga Ramesha Rao; Rana Pratap Singh
Journal:  Evid Based Complement Alternat Med       Date:  2005-02-09       Impact factor: 2.629

9.  Genomic Analysis Highlights the Role of the JAK-STAT Signaling in the Anti-proliferative Effects of Dietary Flavonoid-'Ashwagandha' in Prostate Cancer Cells.

Authors:  Ravikumar Aalinkeel; Zihua Hu; Bindukumar B Nair; Donald E Sykes; Jessica L Reynolds; Supriya D Mahajan; Stanley A Schwartz
Journal:  Evid Based Complement Alternat Med       Date:  2008-01-10       Impact factor: 2.629

10.  Stability indicating studies on NMITLI 118RT+ (standardized extract of withania somnifera dunal).

Authors:  Hafsa Ahmad; Kiran Khandelwal; Shakti Deep Pachauri; Rajender Singh Sanghwan; Anil Kumar Dwivedi
Journal:  Pharmacogn Mag       Date:  2014-07       Impact factor: 1.085
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