Literature DB >> 12622464

Ethanolic extracts of Euphorbia and other ethnobotanical species as inhibitors of human tumour cell growth.

L C Whelan1, M F Ryan.   

Abstract

Ethanolic extracts of 20 plant species, selected from the ethnobotanical literature, were analysed for their pharmacological potential as antineoplastic agents against the HEp-2 cell line. Psoralea corylifolia and E. grandidens were the most efficacious species eliciting IC50 values of 22 microg/ml and 57 microg/ml respectively. Psoralea corylifolia, additionally tested against lung carcinoma (A549) cells gave an IC50 value of 68 microg/ml. Such data would justify a search for active compounds from this species.

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Year:  2003        PMID： 12622464     DOI： 10.1078/094471103321648665

Source DB:  PubMed          Journal:  Phytomedicine        ISSN： 0944-7113            Impact factor:   5.340


  12 in total

1.  Cameroonian medicinal plants: pharmacology and derived natural products.

Authors:  Victor Kuete; Thomas Efferth
Journal:  Front Pharmacol       Date:  2010-10-25       Impact factor: 5.810

2.  Antitumor effect and mechanism of an ellagic acid derivative on the HepG2 human hepatocellular carcinoma cell line.

Authors:  Hui Zhang; Zeng-Jun Guo; Wen-Ming Xu; Xiao-Juan You; Ling Han; Yan-Xia Han; Liu-Jiang Dai
Journal:  Oncol Lett       Date:  2013-12-06       Impact factor: 2.967

3.  Psoralidin induces autophagy through ROS generation which inhibits the proliferation of human lung cancer A549 cells.

Authors:  Wenhui Hao; Xuenong Zhang; Wenwen Zhao; Xiuping Chen
Journal:  PeerJ       Date:  2014-09-09       Impact factor: 2.984

4.  Euphorbia kansui Attenuates Insulin Resistance in Obese Human Subjects and High-Fat Diet-Induced Obese Mice.

Authors:  Seung-Wook Lee; Hyun-Young Na; Mi Hyeon Seol; Mia Kim; Byung-Cheol Lee
Journal:  Evid Based Complement Alternat Med       Date:  2017-10-04       Impact factor: 2.629

Review 5.  Genus Psoralea: A review of the traditional and modern uses, phytochemistry and pharmacology.

Authors:  Bhupendra Koul; Pooja Taak; Arvind Kumar; Anil Kumar; Indraneel Sanyal
Journal:  J Ethnopharmacol       Date:  2018-12-03       Impact factor: 4.360

Review 6.  Flavonoids from the Genus Euphorbia: Isolation, Structure, Pharmacological Activities and Structure-Activity Relationships.

Authors:  Douglas Kemboi Magozwi; Mmabatho Dinala; Nthabiseng Mokwana; Xavier Siwe-Noundou; Rui W M Krause; Molahlehi Sonopo; Lyndy J McGaw; Wilma A Augustyn; Vuyelwa Jacqueline Tembu
Journal:  Pharmaceuticals (Basel)       Date:  2021-05-02

Review 7.  Impact of natural resources and research on cancer treatment and prevention: A perspective from Cameroon.

Authors:  Barnabas Bessem Orang-Ojong; Jose Edward Munyangaju; Ma Shang Wei; Miao Lin; Fan Guan Wei; Charles Foukunang; Yan Zhu
Journal:  Mol Clin Oncol       Date:  2013-05-27

8.  Comparison of the Inhibitory Potential of Bavachalcone and Corylin against UDP-Glucuronosyltransferases.

Authors:  Lina Shan; Shuman Yang; Gang Zhang; Dun Zhou; Zhenyu Qiu; Lei Tian; Hongxia Yuan; Yujun Feng; Xianbao Shi
Journal:  Evid Based Complement Alternat Med       Date:  2014-04-16       Impact factor: 2.629

Review 9.  Phytochemical and Pharmacological Studies on the Genus Psoralea: A Mini Review.

Authors:  Cong-Cong Li; Teng-Long Wang; Zhong-Qun Zhang; Wen-Qiang Yang; Yue-Fei Wang; Xin Chai; Chun-Hua Wang; Zheng Li
Journal:  Evid Based Complement Alternat Med       Date:  2016-11-17       Impact factor: 2.629

10.  Podophyllum hexandrum ameliorates endosulfan-induced genotoxicity and mutagenicity in freshwater cyprinid fish crucian carp.

Authors:  Sabzar Ahmad Dar; Abdul Rehman Yousuf; Masood-Ul-Hassan Balkhi; Bashir Ahmad Ganai; Mudasir Tantry; Farooz Ahmad Bhat
Journal:  Pharm Biol       Date:  2016-10-08       Impact factor: 3.503
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