Literature DB >> 12622244

An overview on the advances of Gymnema sylvestre: chemistry, pharmacology and patents.

E Porchezhian1, R M Dobriyal.   

Abstract

Chemistry and pharmacology of Gymnema sylvestre is reviewed relying on research papers and patent literature. Extracts of this plant are widely used in Australian, Japananese, Vietnamese and Indian folk medicine. Gymnema preparations have a profound action on the modulation of taste, particularly suppressing sweet taste sensations. It is used in the treatment of diabetes mellitus and in food additives against obesity and caries. Anti-allergic, antiviral, lipid lowering and other effects are also reported. From a technological point of view, muchefforts have been made to mask the biter taste of Gymnema preparations.

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Year:  2003        PMID： 12622244

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  12 in total

1.  Molecular mechanisms for sweet-suppressing effect of gymnemic acids.

Authors:  Keisuke Sanematsu; Yuko Kusakabe; Noriatsu Shigemura; Takatsugu Hirokawa; Seiji Nakamura; Toshiaki Imoto; Yuzo Ninomiya
Journal:  J Biol Chem       Date:  2014-07-23       Impact factor: 5.157

Review 2.  Complementary and alternative medicine for the treatment of type 2 diabetes.

Authors:  Richard Nahas; Matthew Moher
Journal:  Can Fam Physician       Date:  2009-06       Impact factor: 3.275

3.  In vitro Inhibitory Effect of Gymnema sylvestre Extracts and Total Gymnemic Acids Fraction on Select Cytochrome P450 Activities in Rat Liver Microsomes.

Authors:  Madhuri Vaghela; Krishna Iyer; Nancy Pandita
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2018-04       Impact factor: 2.441

4.  Gymnemic acid interacts with mammalian glycerol-3-phosphate dehydrogenase.

Authors:  Sumio Ishijima; Tomoyuki Takashima; Tomo Ikemura; Yusuke Izutani
Journal:  Mol Cell Biochem       Date:  2007-12-14       Impact factor: 3.396

5.  Variation in gymnemic acid content and non-destructive harvesting of Gymnema sylvestre (Gudmar).

Authors:  Ashok Kumar Pandey; Swati Yadav
Journal:  Pharmacognosy Res       Date:  2010-09

6.  Immunomodulatory Effect of Gymnema sylvestre (R.Br.) Leaf Extract: An In Vitro Study in Rat Model.

Authors:  Vineet Kumar Singh; Padmanabh Dwivedi; B R Chaudhary; Ramesh Singh
Journal:  PLoS One       Date:  2015-10-16       Impact factor: 3.240

7.  Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells.

Authors:  Gregory Alexander Raciti; Francesca Fiory; Michele Campitelli; Antonella Desiderio; Rosa Spinelli; Michele Longo; Cecilia Nigro; Giacomo Pepe; Eduardo Sommella; Pietro Campiglia; Pietro Formisano; Francesco Beguinot; Claudia Miele
Journal:  PLoS One       Date:  2018-03-29       Impact factor: 3.240

8.  Gymnemic Acids Inhibit Adhesive Nanofibrillar Mediated Streptococcus gordonii-Candida albicans Mono-Species and Dual-Species Biofilms.

Authors:  Raja Veerapandian; Govindsamy Vediyappan
Journal:  Front Microbiol       Date:  2019-10-11       Impact factor: 5.640

9.  Valorizing the 'Irulas' traditional knowledge of medicinal plants in the Kodiakkarai Reserve Forest, India.

Authors:  Subramanyam Ragupathy; Steven G Newmaster
Journal:  J Ethnobiol Ethnomed       Date:  2009-04-14       Impact factor: 2.733

10.  Gymnemic acids inhibit hyphal growth and virulence in Candida albicans.

Authors:  Govindsamy Vediyappan; Vincent Dumontet; Franck Pelissier; Christophe d'Enfert
Journal:  PLoS One       Date:  2013-09-11       Impact factor: 3.240
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