Literature DB >> 12621328

Diagnostic utility of laser-Doppler vibrometry in conductive hearing loss with normal tympanic membrane.

John J Rosowski1, Ritvik P Mehta, Saumil N Merchant.   

Abstract

HYPOTHESIS: It was hypothesized that laser-Doppler vibrometry measurements of umbo velocity in aerated middle ears with conductive loss can differentiate ossicular interruptions, stapes fixations, and mallear fixations. More generally, we hypothesize that laser-Doppler vibrometry measurements of umbo velocity can give information about how differences in the impedance that the ossicles work against affect middle-ear function.
BACKGROUND: Laser-Doppler vibrometry is a well-established research tool for exploring middle-ear function. The authors wished to investigate its potential as a clinical tool for differential diagnosis of the cause of conductive hearing loss.
METHODS: Laser-Doppler vibrometry was used to investigate the relationship between the sound-induced velocity of the tympanic membrane at the umbo and the cause of conductive hearing loss when the tympanic membrane was normal and the middle ear was aerated. The results of measurements in 17 adult ears before exploratory tympanotomy were compared with the surgically determined cause of the hearing loss. The authors also measured the motion of the umbo in 10 patients who had undergone successful small-fenestra stapedectomy procedures. In all the studied ears, pure-tone audiograms were measured at the time of laser-Doppler vibrometry testing.
RESULTS: There were clear statistical differences between the umbo velocity in normal ears and in ears with different ossicular pathologic conditions. There was also a clear separation of the results between ears with ossicular interruptions and ossicular fixation. The pattern of laser-Doppler vibrometry measurements in poststapedectomy ears approximated the pattern in ears with ossicular interruptions.
CONCLUSION: Comparison of laser-Doppler vibrometry results and audiometry may be a sensitive and selective indicator of ossicular pathologic conditions as well as a useful tool for investigating middle ear function.

Entities:  

Mesh:

Year:  2003        PMID: 12621328      PMCID: PMC1464085          DOI: 10.1097/00129492-200303000-00008

Source DB:  PubMed          Journal:  Otol Neurotol        ISSN: 1531-7129            Impact factor:   2.311


  26 in total

1.  Analysis of the best site on the stapes footplate for ossicular chain reconstruction.

Authors:  M Asai; A M Huber; R L Goode
Journal:  Acta Otolaryngol       Date:  1999       Impact factor: 1.494

2.  Wideband reflectance tympanometry in normal adults.

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Journal:  J Acoust Soc Am       Date:  1999-07       Impact factor: 1.840

3.  Evaluation of eardrum laser doppler interferometry as a diagnostic tool.

Authors:  A M Huber; C Schwab; T Linder; S J Stoeckli; M Ferrazzini; N Dillier; U Fisch
Journal:  Laryngoscope       Date:  2001-03       Impact factor: 3.325

4.  Acoustic responses of the human middle ear.

Authors:  S E Voss; J J Rosowski; S N Merchant; W T Peake
Journal:  Hear Res       Date:  2000-12       Impact factor: 3.208

5.  Mass loading on the ossicles and middle ear function.

Authors:  R Z Gan; R K Dyer; M W Wood; K J Dormer
Journal:  Ann Otol Rhinol Laryngol       Date:  2001-05       Impact factor: 1.547

6.  AN EXPERIMENTAL STUDY OF THE ACOUSTIC IMPEDANCE OF THE MIDDLE EAR AND ITS TRANSMISSION PROPERTIES.

Authors:  A R MOLLER
Journal:  Acta Otolaryngol       Date:  1965 Jul-Aug       Impact factor: 1.494

7.  Bone conduction advances following fenestration surgery.

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Journal:  Trans Am Acad Ophthalmol Otolaryngol       Date:  1952 Jul-Aug

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Authors:  A Huber; T Linder; M Ferrazzini; S Schmid; N Dillier; S Stoeckli; U Fisch
Journal:  Ann Otol Rhinol Laryngol       Date:  2001-01       Impact factor: 1.547

9.  Human middle-ear sound transfer function and cochlear input impedance.

Authors:  R Aibara; J T Welsh; S Puria; R L Goode
Journal:  Hear Res       Date:  2001-02       Impact factor: 3.208

10.  Development of wide-band middle ear transmission in the Mongolian gerbil.

Authors:  Edward H Overstreet; Mario A Ruggero
Journal:  J Acoust Soc Am       Date:  2002-01       Impact factor: 1.840

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  28 in total

1.  Measurements of human middle- and inner-ear mechanics with dehiscence of the superior semicircular canal.

Authors:  Wade Chien; Michael E Ravicz; John J Rosowski; Saumil N Merchant
Journal:  Otol Neurotol       Date:  2007-02       Impact factor: 2.311

2.  Distortion product otoacoustic emissions measured as vibration on the eardrum of human subjects.

Authors:  E Dalhoff; D Turcanu; H-P Zenner; A W Gummer
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-22       Impact factor: 11.205

3.  Functional Outcomes of Heparin-Binding Epidermal Growth Factor-Like Growth Factor for Regeneration of Chronic Tympanic Membrane Perforations in Mice.

Authors:  Peter Luke Santa Maria; Peter Gottlieb; Chloe Santa Maria; Sungwoo Kim; Sunil Puria; Yunzhi Peter Yang
Journal:  Tissue Eng Part A       Date:  2017-02-24       Impact factor: 3.845

4.  Investigation of the mechanics of Type III stapes columella tympanoplasty using laser-Doppler vibrometry.

Authors:  Wade Chien; John J Rosowski; Saumil N Merchant
Journal:  Otol Neurotol       Date:  2007-09       Impact factor: 2.311

5.  Optoelectronic holographic otoscope for measurement of nano-displacements in tympanic membranes.

Authors:  Maria Del Socorro Hernández-Montes; Cosme Furlong; John J Rosowski; Nesim Hulli; Ellery Harrington; Jeffrey Tao Cheng; Michael E Ravicz; Fernando Mendoza Santoyo
Journal:  J Biomed Opt       Date:  2009 May-Jun       Impact factor: 3.170

6.  Controlled exploration of the effects of conductive hearing loss on wideband acoustic immittance in human cadaveric preparations.

Authors:  Gabrielle R Merchant; Saumil N Merchant; John J Rosowski; Hideko Heidi Nakajima
Journal:  Hear Res       Date:  2016-08-03       Impact factor: 3.208

7.  Experimental and modeling study of human tympanic membrane motion in the presence of middle ear liquid.

Authors:  Xiangming Zhang; Xiying Guan; Don Nakmali; Vikrant Palan; Mario Pineda; Rong Z Gan
Journal:  J Assoc Res Otolaryngol       Date:  2014-08-09

8.  Long-range, wide-field swept-source optical coherence tomography with GPU accelerated digital lock-in Doppler vibrography for real-time, in vivo middle ear diagnostics.

Authors:  Dan MacDougall; Joshua Farrell; Jeremy Brown; Manohar Bance; Robert Adamson
Journal:  Biomed Opt Express       Date:  2016-10-18       Impact factor: 3.732

9.  [Laser Doppler vibrometric measurements of DPOAE in humans. Eardrum vibrations reflect middle- and inner-ear characteristics].

Authors:  D Turcanu; E Dalhoff; H-P Zenner; A W Gummer
Journal:  HNO       Date:  2007-12       Impact factor: 1.284

10.  Characterizing the ear canal acoustic impedance and reflectance by pole-zero fitting.

Authors:  Sarah R Robinson; Cac T Nguyen; Jont B Allen
Journal:  Hear Res       Date:  2013-03-22       Impact factor: 3.208

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