Literature DB >> 12612642

Integration from proteins to organs: the Physiome Project.

Peter J Hunter1, Thomas K Borg.   

Abstract

The Physiome Project will provide a framework for modelling the human body, using computational methods that incorporate biochemical, biophysical and anatomical information on cells, tissues and organs. The main project goals are to use computational modelling to analyse integrative biological function and to provide a system for hypothesis testing.

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Year:  2003        PMID： 12612642     DOI： 10.1038/nrm1054

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  95 in total

Review 1.  Human cardiac systems electrophysiology and arrhythmogenesis: iteration of experiment and computation.

Authors:  Katherine M Holzem; Eli J Madden; Igor R Efimov
Journal:  Europace       Date:  2014-11       Impact factor: 5.214

2.  Multiphysics simulation of left ventricular filling dynamics using fluid-structure interaction finite element method.

Authors:  Hiroshi Watanabe; Seiryo Sugiura; Hidenobu Kafuku; Toshiaki Hisada
Journal:  Biophys J       Date:  2004-09       Impact factor: 4.033

3.  Verification of cardiac tissue electrophysiology simulators using an N-version benchmark.

Authors:  Steven A Niederer; Eric Kerfoot; Alan P Benson; Miguel O Bernabeu; Olivier Bernus; Chris Bradley; Elizabeth M Cherry; Richard Clayton; Flavio H Fenton; Alan Garny; Elvio Heidenreich; Sander Land; Mary Maleckar; Pras Pathmanathan; Gernot Plank; José F Rodríguez; Ishani Roy; Frank B Sachse; Gunnar Seemann; Ola Skavhaug; Nic P Smith
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2011-11-13       Impact factor: 4.226

Review 4.  Multiscale modeling of gastrointestinal electrophysiology and experimental validation.

Authors:  Peng Du; Greg O'Grady; John B Davidson; Leo K Cheng; Andrew J Pullan
Journal:  Crit Rev Biomed Eng       Date:  2010

Review 5.  Phenomics: the next challenge.

Authors:  David Houle; Diddahally R Govindaraju; Stig Omholt
Journal:  Nat Rev Genet       Date:  2010-12       Impact factor: 53.242

6.  Microcirculation and Hemorheology.

Authors:  Aleksander S Popel; Paul C Johnson
Journal:  Annu Rev Fluid Mech       Date:  2005-01-01       Impact factor: 18.511

7.  In the spotlight: bioinformatics, computational biology and systems biology.

Authors:  May Dongmei Wang
Journal:  IEEE Rev Biomed Eng       Date:  2011

8.  Multi-scale modelling and the IUPS physiome project.

Authors:  Edmund J Crampin; Nicolas P Smith; Peter J Hunter
Journal:  J Mol Histol       Date:  2004-09       Impact factor: 2.611

Review 9.  Modelling biological complexity: a physical scientist's perspective.

Authors:  Peter V Coveney; Philip W Fowler
Journal:  J R Soc Interface       Date:  2005-09-22       Impact factor: 4.118

10.  Composite annotations: requirements for mapping multiscale data and models to biomedical ontologies.

Authors:  Daniel L Cook; Jose L V Mejino; Maxwell L Neal; John H Gennari
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2009
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