Literature DB >> 12612324

Are district general hospital patients with unstable angina at a disadvantage?

C Miller1, K Lipscomb, N Curzen.   

Abstract

OBJECTIVE: To determine whether patients with non-ST elevation acute coronary syndromes requiring coronary angiography and revascularisation have inferior access to these services if admitted to district general hospitals (DGHs) compared with similar patients admitted to a base hospital containing a tertiary cardiac centre.
DESIGN: Prospective, consecutive monitoring of all patients with acute coronary syndromes accepted by the tertiary cardiac centre for angiography and revascularisation over a three month period (1 April to 30 June 2002). PARTICIPANTS: All patients accepted for angiography from DGHs and from within the base hospital with a diagnosis of acute coronary syndromes.
SETTING: Tertiary cardiac facility (Manchester Heart Centre at Manchester Royal Infirmary (MRI)). MAIN OUTCOME MEASURE: Time waited from referral to angiography and revascularisation.
RESULTS: A total of 184 patients with a diagnosis of non-ST elevation acute coronary syndromes underwent angiography with a view to revascularisation. Of these, 89 (48%) were admitted initially to MRI and 95 (52%) were admitted to a feeder DGH. DGH patients waited significantly longer from admission to angiography than MRI patients (median 13 days (25th-75th percentiles 7-19) v 5 days (3-8) respectively; p<0.0005). DGH patients therefore also waited longer from admission to revascularisation (15 days (6-20) v 6 days (3-9) respectively). Once transferred into the Manchester Heart Centre, DGH patients underwent angiography within a median of 1 day (1-2). More DGH patients than those from MRI underwent both coronary artery bypass grafting (21 (22%) v 8 (9%) respectively; p=0.015) and percutaneous coronary intervention (44 (46%) v 32 (36%) respectively; p=NS).
CONCLUSION: Patients admitted to feeder DGHs with non-ST elevation acute coronary syndromes wait significantly longer for access to invasive coronary assessment and revascularisation than similar patients admitted in the hospital that incorporates the tertiary cardiac centre. This inequity of access is determined by postcode rather than clinical priority.

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Year:  2003        PMID: 12612324      PMCID: PMC1742613          DOI: 10.1136/pmj.79.928.93

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  11 in total

Review 1.  Management of acute coronary syndromes: acute coronary syndromes without persistent ST segment elevation; recommendations of the Task Force of the European Society of Cardiology.

Authors:  M E Bertrand; M L Simoons; K A Fox; L C Wallentin; C W Hamm; E McFadden; P J de Feyter; G Specchia; W Ruzyllo
Journal:  Eur Heart J       Date:  2000-09       Impact factor: 29.983

2.  Relation between troponin T and the risk of subsequent cardiac events in unstable coronary artery disease. The FRISC study group.

Authors:  B Lindahl; P Venge; L Wallentin
Journal:  Circulation       Date:  1996-05-01       Impact factor: 29.690

3.  Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban.

Authors:  C P Cannon; W S Weintraub; L A Demopoulos; R Vicari; M J Frey; N Lakkis; F J Neumann; D H Robertson; P T DeLucca; P M DiBattiste; C M Gibson; E Braunwald
Journal:  N Engl J Med       Date:  2001-06-21       Impact factor: 91.245

4.  Clinical outcomes, risk stratification and practice patterns of unstable angina and myocardial infarction without ST elevation: Prospective Registry of Acute Ischaemic Syndromes in the UK (PRAIS-UK)

Authors:  J Collinson; M D Flather; K A Fox; I Findlay; E Rodrigues; P Dooley; P Ludman; J Adgey; T J Bowker; R Mattu
Journal:  Eur Heart J       Date:  2000-09       Impact factor: 29.983

5.  Prognostic value of ST segment depression in acute coronary syndromes: insights from PARAGON-A applied to GUSTO-IIb. PARAGON-A and GUSTO IIb Investigators. Platelet IIb/IIIa Antagonism for the Reduction of Acute Global Organization Network.

Authors:  P Kaul; Y Fu; W C Chang; R A Harrington; G S Wagner; S G Goodman; C B Granger; D J Moliterno; F Van de Werf; R M Califf; E J Topol; P W Armstrong
Journal:  J Am Coll Cardiol       Date:  2001-07       Impact factor: 24.094

6.  ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina).

Authors:  E Braunwald; E M Antman; J W Beasley; R M Califf; M D Cheitlin; J S Hochman; R H Jones; D Kereiakes; J Kupersmith; T N Levin; C J Pepine; J W Schaeffer; E E Smith; D E Steward; P Theroux; J S Alpert; K A Eagle; D P Faxon; V Fuster; T J Gardner; G Gregoratos; R O Russell; S C Smith
Journal:  J Am Coll Cardiol       Date:  2000-09       Impact factor: 24.094

7.  Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. FRISC II Investigators. Fast Revascularisation during Instability in Coronary artery disease.

Authors:  L Wallentin; B Lagerqvist; S Husted; F Kontny; E Ståhle; E Swahn
Journal:  Lancet       Date:  2000-07-01       Impact factor: 79.321

8.  Prospective study of the role of cardiac troponin T in patients admitted with unstable angina.

Authors:  P Stubbs; P Collinson; D Moseley; T Greenwood; M Noble
Journal:  BMJ       Date:  1996-08-03

9.  Variations between countries in invasive cardiac procedures and outcomes in patients with suspected unstable angina or myocardial infarction without initial ST elevation. OASIS (Organisation to Assess Strategies for Ischaemic Syndromes) Registry Investigators.

Authors:  S Yusuf; M Flather; J Pogue; D Hunt; J Varigos; L Piegas; A Avezum; J Anderson; M Keltai; A Budaj; K Fox; L Ceremuzynski
Journal:  Lancet       Date:  1998-08-15       Impact factor: 79.321

10.  Incidence and follow-up of Braunwald subgroups in unstable angina pectoris.

Authors:  A J van Miltenburg-van Zijl; M L Simoons; R J Veerhoek; P M Bossuyt
Journal:  J Am Coll Cardiol       Date:  1995-05       Impact factor: 24.094

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  3 in total

1.  Reducing transfer times for coronary angiography in patients with acute coronary syndromes: one solution to a national problem.

Authors:  N G Bellenger; T Wells; R Hitchcock; M Watkins; C Duffet; D Jewell; D Palliser; L Shapland; R Curtis; S Scrase; R Burns; N Curzen
Journal:  Postgrad Med J       Date:  2006-06       Impact factor: 2.401

2.  Troponin in patients with chest pain.

Authors:  N Curzen
Journal:  BMJ       Date:  2004-12-11

3.  Non-clinical factors influencing the selection of patients with acute coronary syndromes for angiography.

Authors:  A Quaas; N Curzen; C Garratt
Journal:  Postgrad Med J       Date:  2004-07       Impact factor: 2.401

  3 in total

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