Literature DB >> 12611822

Concomitant psychotropic medication for youths.

Daniel J Safer1, Julie Magno Zito, Susan DosReis.   

Abstract

OBJECTIVE: This study reviewed the clinical research and practice literature relating to the prevalence and patterns of concomitant psychotropic medication given to youths with emotional and behavioral disorders.
METHOD: A MEDLINE search from 1996 through spring 2002, including a review of references from relevant published articles and reports, was undertaken to identify available information on concomitant psychotropic medication for youths.
RESULTS: The data supporting concomitant psychotropic medication for youths are almost exclusively based on case reports and small-scale, nonblind assessments. In the mid-1990s, over 20% of outpatient youths treated in community mental health centers and over 40% of youths treated in inpatient psychiatric facilities were given concomitant psychotropic medication. The rate has since increased. Psychiatrists more than primary care physicians prescribe concomitant psychotropic medication, and they show great variability in their prescribing habits. Youths with aggressive behavior, male gender, severe emotional illness, and disabling social maladjustment are most likely to receive concomitant psychotropic medication.
CONCLUSIONS: Substantive systematic evidence is needed to clarify this increasingly common, inadequately researched child psychopharmacologic practice.

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Year:  2003        PMID: 12611822     DOI: 10.1176/appi.ajp.160.3.438

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  41 in total

Review 1.  Efficacy and safety of antidepressants for children and adolescents.

Authors:  Jon N Jureidini; Christopher J Doecke; Peter R Mansfield; Michelle M Haby; David B Menkes; Anne L Tonkin
Journal:  BMJ       Date:  2004-04-10

2.  Multiple psychiatric diagnoses common in privately insured children on atypical antipsychotics.

Authors:  Donna R Halloran; Jason Swindle; Steve K Takemoto; Mark A Schnitzler
Journal:  Clin Pediatr (Phila)       Date:  2010-01-28       Impact factor: 1.168

3.  Pediatric psychotropic polypharmacy.

Authors:  Mark R Zonfrillo; Joseph V Penn; Henrietta L Leonard
Journal:  Psychiatry (Edgmont)       Date:  2005-08

4.  Juvenile administration of concomitant methylphenidate and fluoxetine alters behavioral reactivity to reward- and mood-related stimuli and disrupts ventral tegmental area gene expression in adulthood.

Authors:  Brandon L Warren; Sergio D Iñiguez; Lyonna F Alcantara; Katherine N Wright; Eric M Parise; Sarah K Weakley; Carlos A Bolaños-Guzmán
Journal:  J Neurosci       Date:  2011-07-13       Impact factor: 6.167

Review 5.  Potential adverse effects of amphetamine treatment on brain and behavior: a review.

Authors:  S M Berman; R Kuczenski; J T McCracken; E D London
Journal:  Mol Psychiatry       Date:  2008-08-12       Impact factor: 15.992

6.  Effects of psychotropic drugs on second messenger signaling and preference for nicotine in juvenile male mice.

Authors:  Lyonna F Alcantara; Brandon L Warren; Eric M Parise; Sergio D Iñiguez; Carlos A Bolaños-Guzmán
Journal:  Psychopharmacology (Berl)       Date:  2014-01-23       Impact factor: 4.530

7.  Trends in psychotropic polypharmacy among youths enrolled in Ohio Medicaid, 2002-2008.

Authors:  Cynthia A Fontanella; Lynn A Warner; Gary S Phillips; Jeffrey A Bridge; John V Campo
Journal:  Psychiatr Serv       Date:  2014-10-31       Impact factor: 3.084

8.  The 5-HT1B serotonin receptor regulates methylphenidate-induced gene expression in the striatum: Differential effects on immediate-early genes.

Authors:  David Alter; Joel A Beverley; Ronak Patel; Carlos A Bolaños-Guzmán; Heinz Steiner
Journal:  J Psychopharmacol       Date:  2017-07-18       Impact factor: 4.153

9.  Community child psychiatric medication experiences measured by an internet-based, prospective parent survey of retail pharmacy customers.

Authors:  Robert Hilt; Christine Wolf; Kent Koprowicz; Elizabeth Thomas; Mary Chandler; Xiao Lei Hao; Matthew Russell; Tung Le; Lee Hooks; Bryan King
Journal:  Community Ment Health J       Date:  2013-12-10

10.  Aberrant Behaviors and Co-occurring Conditions as Predictors of Psychotropic Polypharmacy among Children with Autism Spectrum Disorders.

Authors:  Sarah L Logan; Laura Carpenter; R Scott Leslie; Elizabeth Garrett-Mayer; Kelly J Hunt; Jane Charles; Joyce S Nicholas
Journal:  J Child Adolesc Psychopharmacol       Date:  2015-04-28       Impact factor: 2.576

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