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Literature DB >> 12608870

Rigidins B-D, new pyrrolopyrimidine alkaloids from a tunicate Cystodytes species.

Masashi Tsuda¹, Kohei Nozawa, Kazutaka Shimbo, Jun'ichi Kobayashi.

Abstract

Three new pyrrolopyrimidine alkaloids, rigidins B-D (1-3), have been isolated from an Okinawan marine tunicate Cystodytes sp., and the structures were elucidated on the basis of spectroscopic data.

Entities: Chemical

Mesh：

Substances：

Year: 2003 PMID： 12608870 DOI： 10.1021/np020393a

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

10 in total

1. Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins: Exploration of the N3 and N9 Positions and Interaction with Multidrug-Resistance Proteins.

Authors: Ramesh Dasari; Andrzej Błauż; Derek C Medellin; Roaa M Kassim; Carlos Viera; Maximo Santarosa; Alet E van der Westhuyzen; Willem A L van Otterlo; Taryn Olivas; Tugba Yildiz; Tania Betancourt; Charles B Shuster; Snezna Rogelj; Błażej Rychlik; Todd Hudnall; Liliya V Frolova; Alexander Kornienko
Journal: ChemMedChem Date: 2019-01-25 Impact factor: 3.466

Review 2. Biosynthesis of pyrrolopyrimidines.

Authors: Reid M McCarty; Vahe Bandarian
Journal: Bioorg Chem Date: 2012-01-31 Impact factor: 5.275

3. One-pot multicomponent synthesis of diversely substituted 2-aminopyrroles. A short general synthesis of rigidins A, B, C, and D.

Authors: Liliya V Frolova; Nikolai M Evdokimov; Kathryn Hayden; Indranil Malik; Snezna Rogelj; Alexander Kornienko; Igor V Magedov
Journal: Org Lett Date: 2011-01-26 Impact factor: 6.005

4. Exploring natural product chemistry and biology with multicomponent reactions. 5. Discovery of a novel tubulin-targeting scaffold derived from the rigidin family of marine alkaloids.

Authors: Liliya V Frolova; Igor V Magedov; Anntherese E Romero; Menuka Karki; Isaiah Otero; Kathryn Hayden; Nikolai M Evdokimov; Laetitia Moreno Y Banuls; Shiva K Rastogi; W Ross Smith; Shi-Long Lu; Robert Kiss; Charles B Shuster; Ernest Hamel; Tania Betancourt; Snezna Rogelj; Alexander Kornienko
Journal: J Med Chem Date: 2013-08-23 Impact factor: 7.446

5. Synthetic and biological studies of tubulin targeting c2-substituted 7-deazahypoxanthines derived from marine alkaloid rigidins.

Authors: Robert Scott; Menuka Karki; Mary R Reisenauer; Roberta Rodrigues; Ramesh Dasari; W Ross Smith; Stephen C Pelly; Willem A L van Otterlo; Charles B Shuster; Snezna Rogelj; Igor V Magedov; Liliya V Frolova; Alexander Kornienko
Journal: ChemMedChem Date: 2014-03-18 Impact factor: 3.466

Review 6. Marine Pyrrole Alkaloids.

Authors: Kevin Seipp; Leander Geske; Till Opatz
Journal: Mar Drugs Date: 2021-09-10 Impact factor: 5.118

Rigidins B-D, new pyrrolopyrimidine alkaloids from a tunicate Cystodytes species.

1. Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins: Exploration of the N3 and N9 Positions and Interaction with Multidrug-Resistance Proteins.

Review 2. Biosynthesis of pyrrolopyrimidines.

3. One-pot multicomponent synthesis of diversely substituted 2-aminopyrroles. A short general synthesis of rigidins A, B, C, and D.

4. Exploring natural product chemistry and biology with multicomponent reactions. 5. Discovery of a novel tubulin-targeting scaffold derived from the rigidin family of marine alkaloids.

5. Synthetic and biological studies of tubulin targeting c2-substituted 7-deazahypoxanthines derived from marine alkaloid rigidins.

Review 6. Marine Pyrrole Alkaloids.

Review 7. Bioactive dehydrotyrosyl and dehydrodopyl compounds of marine origin.

8. Total synthesis of a marine alkaloid--rigidin E.

Review 9. Anticancer properties of lamellarins.

10. Retracted Article: The synthesis and biological activity of marine alkaloid derivatives and analogues.