Literature DB >> 12608823

Two novel cytotoxic cyclodepsipeptides from a mycoparasitic Cladobotryum sp.

Yunjiang Feng1, John W Blunt, Anthony L J Cole, John F Cannon, Ward T Robinson, Murray H G Munro.   

Abstract

Two novel cyclodepsipeptides (1 and 2) along with three known compounds (3-5) were isolated from a New Zealand isolate of a Cladobotryum sp. The structures of 1 and 2 were elucidated from NMR and HRESIMS experiments, and the absolute stereochemistry of 2 was established by X-ray crystallography and chemical degradation. Compounds 1 and 2 were both cytotoxic against murine P388 leukemia cells.

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Year:  2003        PMID: 12608823     DOI: 10.1021/jo0263059

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  5 in total

Review 1.  Structural Diversity and Biological Activities of Fungal Cyclic Peptides, Excluding Cyclodipeptides.

Authors:  Xiaohan Wang; Minyi Lin; Dan Xu; Daowan Lai; Ligang Zhou
Journal:  Molecules       Date:  2017-11-27       Impact factor: 4.411

2.  Cladobotric Acids: Metabolites from Cultures of Cladobotryum sp., Semisynthetic Analogues and Antibacterial Activity.

Authors:  Trong-Tuan Dao; Katherine Williams; Kate M J de Mattos-Shipley; Zhongshu Song; Yuiko Takebayashi; Thomas J Simpson; James Spencer; Andrew M Bailey; Christine L Willis
Journal:  J Nat Prod       Date:  2022-02-16       Impact factor: 4.803

3.  Polyphasic Systematics of the Fungicolous Genus Cladobotryum Based on Morphological, Molecular and Metabolomics Data.

Authors:  Nikola Milic; Anastasia C Christinaki; Dimitra Benaki; Aimilia A Stavrou; Nikolaos Tsafantakis; Nikolas Fokialakis; Vassili N Kouvelis; Zacharoula Gonou-Zagou
Journal:  J Fungi (Basel)       Date:  2022-08-20

4.  Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin IV and chetracin B.

Authors:  Ghada A Ebead; David P Overy; Fabrice Berrué; Russell G Kerr
Journal:  IMA Fungus       Date:  2012-12-11       Impact factor: 3.515

Review 5.  Structural Diversity and Biological Activities of Cyclic Depsipeptides from Fungi.

Authors:  Xiaohan Wang; Xiao Gong; Peng Li; Daowan Lai; Ligang Zhou
Journal:  Molecules       Date:  2018-01-15       Impact factor: 4.411

  5 in total

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