PURPOSE: This study tests the possibility of using synchrotron radiation (SR) x-ray micro-imaging as a new method to evaluate osseointegration. MATERIALS AND METHODS: A simple imaging setup with primarily unmonochromatic SR was used to study the interface of a dental implant in contact with bone. The samples were prepared by sectioning the undecalcified specimen of a titanium screw implanted in the tibia of a New Zealand white rabbit. Radiographs of the interface between surrounding tissues and dental titanium implant were imaged using the SR imaging system at PLS (Pohang Light Source) 5C1 beamline, a micro-computed tomography (microCT) system (SkyScan-1072), and a conventional dental x-ray system (Siemens Heliodent MD). RESULTS: The image quality of the osseointegrated titanium implant was compared among the 3 imaging systems. The SR imaging technique showed greater details than other radiographic modalities for evaluation of the healing stage of bone-implant contact. DISCUSSION: The evaluation was especially focused on the image quality of the osseous contact at the bone-to-implant interfaces. CONCLUSIONS: This SR imaging technique provides finer details and can be expected to make an impact in the clinical study of osseointegration.
PURPOSE: This study tests the possibility of using synchrotron radiation (SR) x-ray micro-imaging as a new method to evaluate osseointegration. MATERIALS AND METHODS: A simple imaging setup with primarily unmonochromatic SR was used to study the interface of a dental implant in contact with bone. The samples were prepared by sectioning the undecalcified specimen of a titanium screw implanted in the tibia of a New Zealand white rabbit. Radiographs of the interface between surrounding tissues and dental titanium implant were imaged using the SR imaging system at PLS (Pohang Light Source) 5C1 beamline, a micro-computed tomography (microCT) system (SkyScan-1072), and a conventional dental x-ray system (Siemens Heliodent MD). RESULTS: The image quality of the osseointegrated titanium implant was compared among the 3 imaging systems. The SR imaging technique showed greater details than other radiographic modalities for evaluation of the healing stage of bone-implant contact. DISCUSSION: The evaluation was especially focused on the image quality of the osseous contact at the bone-to-implant interfaces. CONCLUSIONS: This SR imaging technique provides finer details and can be expected to make an impact in the clinical study of osseointegration.
Authors: Qiang Fu; Wenhai Huang; Weitao Jia; Mohamed N Rahaman; Xin Liu; Antoni P Tomsia Journal: Tissue Eng Part A Date: 2011-08-29 Impact factor: 3.845