Literature DB >> 12605495

Probing the diastereotopicity of methylene protons in strychnine using residual dipolar couplings.

Christina M Thiele1, Stefan Berger.   

Abstract

Residual dipolar couplings were successfully used to distinguish between the two diastereotopic protons on C-20 of strychnine dissolved in an organic liquid crystal (PBLG/CDCl(3)). The results presented here strongly suggest that this method will be of help in organic structure determination, making the determination of relative stereochemistry in the absence of NOE data possible.

Entities:  

Year:  2003        PMID： 12605495     DOI： 10.1021/ol0275163

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

1.  J-Spectroscopy in the presence of residual dipolar couplings: determination of one-bond coupling constants and scalable resolution.

Authors:  Julien Furrer; Michael John; Horst Kessler; Burkhard Luy
Journal:  J Biomol NMR       Date:  2007-01-19       Impact factor: 2.835

2.  Structural discrimination in small molecules by accurate measurement of long-range proton-carbon NMR residual dipolar couplings.

Authors:  Pablo Trigo-Mouriño; Armando Navarro-Vázquez; Jinfa Ying; Roberto R Gil; Ad Bax
Journal:  Angew Chem Int Ed Engl       Date:  2011-07-12       Impact factor: 15.336

3.  Challenge of large-scale motion for residual dipolar coupling based analysis of configuration: the case of fibrosterol sulfate A.

Authors:  Han Sun; Uwe M Reinscheid; Emily L Whitson; Edward J d'Auvergne; Chris M Ireland; Armando Navarro-Vázquez; Christian Griesinger
Journal:  J Am Chem Soc       Date:  2011-08-23       Impact factor: 15.419

Review 4.  Residual Dipolar Couplings in Structure Determination of Natural Products.

Authors:  Gao-Wei Li; Han Liu; Feng Qiu; Xiao-Juan Wang; Xin-Xiang Lei
Journal:  Nat Prod Bioprospect       Date:  2018-06-25

5.  Configuration determination by residual dipolar couplings: accessing the full conformational space by molecular dynamics with tensorial constraints.

Authors:  Pavleta Tzvetkova; Ulrich Sternberg; Thomas Gloge; Armando Navarro-Vázquez; Burkhard Luy
Journal:  Chem Sci       Date:  2019-07-29       Impact factor: 9.825

6.  Synthesis of lanthanide tag and experimental studies on paramagnetically induced residual dipolar couplings.

Authors:  Ali Yassin; Bilal Nehmeh; Sally El Kantar; Yara Al Kazzaz; Elias Akoury
Journal:  BMC Chem       Date:  2022-07-21
  6 in total

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