Literature DB >> 12596112

Appendicitis in children: a ten-year update of therapeutic recommendations.

Sherif Emil1, Jean-Martin Laberge, Peter Mikhail, Livia Baican, Helene Flageole, Luong Nguyen, Kenneth Shaw.   

Abstract

BACKGROUND/
PURPOSE: In 1990, the authors reported excellent outcomes using a standard protocol to treat pediatric appendicitis. This protocol has been simplified further and a large retrospective review was conducted to assess current outcomes.
METHODS: All patients treated for presumed appendicitis between April 1997 and December 1999 were reviewed. All patients received preoperative gentamicin and clindamycin. Patients with complicated appendicitis received postoperative ampicillin, gentamicin, and clindamycin or metronidazole. All wounds were closed primarily without drains. Patients with complicated appendicitis were discharged when their ileus resolved, they remained afebrile for 24 hours, and had a normal leukocyte count.
RESULTS: A total of 648 patients were reviewed. A total of 9.4% of appendices were pathologically normal, 55.6% were simple acute, 15.7% were gangrenous, and 19.3% were perforated. Hospital stay was 2.21 +/- 2.04 days for normal, 1.39 +/-.89 for simple acute, 2.97 +/- 1.25 for gangrenous, and 6.31 +/- 3.51 days for perforated appendices. There were no wound infections in patients with normal or simple acute appendices. Two minor intraabdominal infections (0.56%) occurred in patients with simple appendicitis. Patients with complicated appendicitis (gangrenous or perforated) had wound infection and intraabdominal infection rates of 2.6% and 4.4%, respectively.
CONCLUSIONS: The authors' current protocol results in reasonable hospital stays and good outcomes. It serves as an evidence-based standard of care for the treatment of pediatric appendicitis. Copyright 2003, Elsevier Science (USA). All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 12596112     DOI: 10.1053/jpsu.2003.50052

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  19 in total

1.  Determinants of postoperative abscess occurrence and percutaneous drainage in children with perforated appendicitis.

Authors:  Sherif Emil; Sherif Elkady; Layla Shbat; Fouad Youssef; Robert Baird; Jean-Martin Laberge; Pramod Puligandla; Kenneth Shaw
Journal:  Pediatr Surg Int       Date:  2014-11-02       Impact factor: 1.827

2.  Rapid non-contrast magnetic resonance imaging for post appendectomy intra-abdominal abscess in children.

Authors:  Megan H Lee; Eric P Eutsler; Elizabeth F Sheybani; Geetika Khanna
Journal:  Pediatr Radiol       Date:  2017-04-20

3.  Lack of benefit of preoperative antimicrobial prophylaxis in children with acute appendicitis: a prospective cohort study.

Authors:  V Bansal; S Altermatt; D Nadal; C Berger
Journal:  Infection       Date:  2012-07-19       Impact factor: 3.553

4.  Comparison of Antibiotic Therapy and Appendectomy for Acute Uncomplicated Appendicitis in Children: A Meta-analysis.

Authors:  Libin Huang; Yuan Yin; Lie Yang; Cun Wang; Yuan Li; Zongguang Zhou
Journal:  JAMA Pediatr       Date:  2017-05-01       Impact factor: 16.193

Review 5.  Primary versus delayed wound closure in complicated appendicitis: an international systematic review and meta-analysis.

Authors:  Marion C W Henry; R Lawrence Moss
Journal:  Pediatr Surg Int       Date:  2005-10-13       Impact factor: 1.827

6.  Acute appendicitis in preschool-age children.

Authors:  George Sakellaris; Stefanos Tilemis; Giorgos Charissis
Journal:  Eur J Pediatr       Date:  2004-11-20       Impact factor: 3.183

7.  Drainage vs no drainage in secondary peritonitis with sepsis following complicated appendicitis in adults in the modern era of antibiotics.

Authors:  Sheraz Ahmed Rather; Shams Ul Bari; Ajaz A Malik; Asima Khan
Journal:  World J Gastrointest Surg       Date:  2013-11-27

8.  Open appendectomy for pediatric ruptured appendicitis: a historical clinical review of the prophylaxis of wound infection and postoperative intra-abdominal abscess.

Authors:  Sigmund H Ein; Ahmed Nasr; Arlene Ein
Journal:  Can J Surg       Date:  2013-06       Impact factor: 2.089

9.  Evidence-based adjustment of antibiotic in pediatric complicated appendicitis in the era of antibiotic resistance.

Authors:  Kin Wai Edwin Chan; Kim Hung Lee; Jennifer Wai Cheung Mou; Sing Tak Cheung; Jennifer Dart Yin Sihoe; Yuk Him Tam
Journal:  Pediatr Surg Int       Date:  2010-02       Impact factor: 1.827

10.  Province-wide population survey of acute appendicitis in Canada. New twists to an old disease.

Authors:  J-P Gagné; M Billard; R Gagnon; M Laurion; A Jacques
Journal:  Surg Endosc       Date:  2007-02-16       Impact factor: 4.584

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.