Literature DB >> 1259515

Stoffwechselprodukte von mikroorganismen. 154. Mitteilung. Nikkomycin, ein neuer hemmstoff der chitinsynthese bei pilzen.

U Dähn, H Hagenmaier, H Höhne, W A König, G Wolf, H Zähner.   

Abstract

From the fermentation broth of Streptomyces tendae Tü 901 a substance was isolated which inhibits the growth of several fungi. The new antibiotic affects the chitchin biosynthesis. Its structure was identified by mass spectrometry of the products obtained after chemical degradation. Nikkomycin is a nucleoside-peptide antibiotic consisting of uracil, an amino hexuronic acid and a new amino acid containing a pyridin ring.

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Year:  1976        PMID： 1259515     DOI： 10.1007/BF00446834

Source DB:  PubMed          Journal:  Arch Microbiol        ISSN： 0302-8933            Impact factor:   2.552


  28 in total

1.  The synthesis of chitin in cell-free extracts of Neurospora crassa.

Authors:  L GLASER; D H BROWN
Journal:  J Biol Chem       Date:  1957-10       Impact factor: 5.157

2.  Phosphoacetylglucosamine mutase of Neurospora.

Authors:  J L REISSIG
Journal:  J Biol Chem       Date:  1956-04       Impact factor: 5.157

3.  The biosynthesis of glucosamine.

Authors:  L F LELOIR; C E CARDINI
Journal:  Biochim Biophys Acta       Date:  1953 Sep-Oct

4.  THE ENZYMATIC SYNTHESIS IN VITRO OF HYALURONIC ACID CHAINS.

Authors:  L Glaser; D H Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1955-05-15       Impact factor: 11.205

5.  Metabolic products of microorganisms 123. Thraustomycin, a new antifungal nucleoside antibiotic from Streptomyces exfoliatus.

Authors:  H Kneifel; W A König; G Wolf; H Zähner
Journal:  J Antibiot (Tokyo)       Date:  1974-01       Impact factor: 2.649

6.  [Metabolic products of microorganisms. 5l. On the mechanism of action of borrelidin-inhibition of the threonine incorporation in sRNA].

Authors:  R Hütter; K Poralla; H G Zachau; H Zähner
Journal:  Biochem Z       Date:  1966-03-28

7.  [Mass spectrometry of adenosine analogues].

Authors:  W A König; K Zech; R Uhmann; W Voelter
Journal:  Chem Ber       Date:  1972

8.  Studies on polyoxins, antifungal antibiotics. 13. The structure of polyoxins.

Authors:  K Isono; K Asahi; S Suzuki
Journal:  J Am Chem Soc       Date:  1969-12-17       Impact factor: 15.419

9.  Pathway of chitin synthesis and cellular localization of chitin synthetase in Mocor rouxii.

Authors:  I McMurrough; A Flores-Carreon; S Bartnicki-Garcia
Journal:  J Biol Chem       Date:  1971-06-25       Impact factor: 5.157

10.  Ribonucleic acid synthesis in yeast. The effect of cycloheximide on the synthesis of ribonucleic acid in Saccharomyces carlsbergensis.

Authors:  S R de Kloet
Journal:  Biochem J       Date:  1966-06       Impact factor: 3.857
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  34 in total

1.  Effects of oxygen supply on the production of nikkomycin with immobilized cells of Streptomyces tendae.

Authors:  H U Trück; H Chmiel; W P Hammes; W Trösch
Journal:  Appl Microbiol Biotechnol       Date:  1990-10       Impact factor: 4.813

2.  Structural and functional characterization of NikO, an enolpyruvyl transferase essential in nikkomycin biosynthesis.

Authors:  Gustav Oberdorfer; Alexandra Binter; Cristian Ginj; Peter Macheroux; Karl Gruber
Journal:  J Biol Chem       Date:  2012-07-18       Impact factor: 5.157

3.  Physiology and nutritional aspects of actinomycetes: an overview.

Authors:  M C Srinivasan; R S Laxman; M V Deshpande
Journal:  World J Microbiol Biotechnol       Date:  1991-03       Impact factor: 3.312

4.  Chitin synthetase from yeast-type cells ofMucor rouxii induced by malonic acid: a screen for antifungal agents and isolation of an active metabolite from an actinomycetes.

Authors:  P J Zou; X M Lo; Y X Song; D K Song
Journal:  World J Microbiol Biotechnol       Date:  1990-06       Impact factor: 3.312

5.  Isolation and structural determination of a new antibacterial compound demethyl-L-681,217 from Streptomyces cattleya.

Authors:  Shogo Sugai; Hisayuki Komaki; Hikaru Hemmi; Shinya Kodani
Journal:  J Antibiot (Tokyo)       Date:  2016-05-25       Impact factor: 2.649

Review 6.  Recent advances in the understanding of the Aspergillus fumigatus cell wall.

Authors:  Mark J Lee; Donald C Sheppard
Journal:  J Microbiol       Date:  2016-02-27       Impact factor: 3.422

Review 7.  Insect chitin synthases: a review.

Authors:  Hans Merzendorfer
Journal:  J Comp Physiol B       Date:  2005-08-02       Impact factor: 2.200

8.  Evaluation of nikkomycins X and Z in murine models of coccidioidomycosis, histoplasmosis, and blastomycosis.

Authors:  R F Hector; B L Zimmer; D Pappagianis
Journal:  Antimicrob Agents Chemother       Date:  1990-04       Impact factor: 5.191

9.  A practical and scalable manufacturing process for an anti-fungal agent, Nikkomycin Z.

Authors:  Christopher J Stenland; Lev G Lis; Frederick J Schendel; Nicholas J Hahn; Mary A Smart; Amy L Miller; Marc G von Keitz; Vadim J Gurvich
Journal:  Org Process Res Dev       Date:  2013-01-17       Impact factor: 3.317

10.  Biological properties and mode of action of clavams.

Authors:  F Röhl; J Rabenhorst; H Zähner
Journal:  Arch Microbiol       Date:  1987-05       Impact factor: 2.552
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