Literature DB >> 12591210

Auditory amplification: outer hair cells pres the issue.

Gwénaëlle S G Géléoc1, Jeffrey R Holt.   

Abstract

Active feedback mechanisms in the ears of mammals amplify and tune the auditory response to sound stimuli, allowing these organisms to enjoy both exquisite sensitivity and sharp frequency selectivity. A requisite component of this feedback pathway has recently been identified. Targeted deletion of pres, the gene that encodes the novel membrane-bound motor protein prestin, has revealed a hundred-fold loss in hearing sensitivity suggesting that it might be part of the elusive cochlear amplifier.

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Year:  2003        PMID: 12591210     DOI: 10.1016/S0166-2236(03)00030-4

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN: 0166-2236            Impact factor:   13.837


  9 in total

1.  Voltage-sensitive prestin orthologue expressed in zebrafish hair cells.

Authors:  Jörg T Albert; Harald Winter; Thorsten J Schaechinger; Thomas Weber; Xiang Wang; David Z Z He; Oliver Hendrich; Hyun-Soon Geisler; Ulrike Zimmermann; Katrin Oelmann; Marlies Knipper; Martin C Göpfert; Dominik Oliver
Journal:  J Physiol       Date:  2007-02-01       Impact factor: 5.182

Review 2.  Silencing the cochlear amplifier by immobilizing prestin.

Authors:  Ulrich Müller; Peter Gillespie
Journal:  Neuron       Date:  2008-05-08       Impact factor: 17.173

Review 3.  Otoacoustic emissions from insect ears: evidence of active hearing?

Authors:  Manfred Kössl; Doreen Möckel; Melanie Weber; Ernst-August Seyfarth
Journal:  J Comp Physiol A Neuroethol Sens Neural Behav Physiol       Date:  2008-05-31       Impact factor: 1.836

Review 4.  Inner ear organoids: new tools to understand neurosensory cell development, degeneration and regeneration.

Authors:  Marta Roccio; Albert S B Edge
Journal:  Development       Date:  2019-09-02       Impact factor: 6.868

5.  Effect of myricetin on the gene expressions of NOX3, TGF-β1, prestin, and HSP-70 and anti-oxidant activity in the cochlea of noise-exposed rats.

Authors:  Maryam Bahaloo; Mohammad Ebrahim Rezvani; Ehsan Farashahi Yazd; Fatemeh Zare Mehrjerdi; Mohammad Hossein Davari; Ali Roohbakhsh; Abolfazl Mollasadeghi; Haniyeh Nikkhah; Maryam Vafaei; Amir Houshang Mehrparvar
Journal:  Iran J Basic Med Sci       Date:  2020-05       Impact factor: 2.699

Review 6.  Prestin and the cholinergic receptor of hair cells: positively-selected proteins in mammals.

Authors:  Ana Belén Elgoyhen; Lucía F Franchini
Journal:  Hear Res       Date:  2010-01-06       Impact factor: 3.208

7.  Cochlear function in Prestin knockout mice.

Authors:  M A Cheatham; K H Huynh; J Gao; J Zuo; P Dallos
Journal:  J Physiol       Date:  2004-08-19       Impact factor: 5.182

8.  A role for the canonical nuclear factor-κB pathway in coupling neurotrophin-induced differential survival of developing spiral ganglion neurons.

Authors:  Renaud Vandenbosch; Eva Chocholova; Pierre A Robe; Yiqiao Wang; Cécile Lambert; Gustave Moonen; François Lallemend; Brigitte Malgrange; Saïda Hadjab
Journal:  Front Cell Neurosci       Date:  2013-11-28       Impact factor: 5.505

9.  Loss of the Cochlear Amplifier Prestin Reduces Temporal Processing Efficacy in the Central Auditory System.

Authors:  Joseph P Walton; Adam C Dziorny; Olga N Vasilyeva; Anne E Luebke
Journal:  Front Cell Neurosci       Date:  2018-09-21       Impact factor: 5.505

  9 in total

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