Literature DB >> 12585976

Post-kala-azar dermal leishmaniasis associated with AIDS.

Achiléa Bittencourt1, Nancy Silva, Andréa Straatmann, Victor Luiz Correia Nunes, Ivonise Follador, Roberto Badaró.   

Abstract

Post-kala-azar dermal leishmaniasis (PKDL) is rarely reported in South America. In spite of the fact that there are many reports about the association of visceral leishmaniasis and AIDS, PKDL is very uncommon in HIV-positive patients, and so far only four cases have been documented in the literature. We present another case with unusual clinicopathological aspects. The patient, a 28-year-old male, from Salvador, Bahia (an endemic area) presented with clinical manifestations of visceral leishmaniasis three years after the diagnosis of AIDS. During treatment for visceral leishmaniasis he developed disseminated miliary papules. Microscopically, the skin biopsy showed a "saw-tooth" pattern with a lichenoid mononuclear infiltrate simulating lichen planus. The histopathological diagnosis was achieved through the finding of amastigotes. The authors discuss the clinicopathological aspects of this case based on a review of the specific literature.

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Year:  2003        PMID: 12585976     DOI: 10.1590/s1413-86702002000600008

Source DB:  PubMed          Journal:  Braz J Infect Dis        ISSN: 1413-8670            Impact factor:   1.949


  6 in total

1.  Disseminated cutaneous leishmaniasis resembling post-kala-azar dermal leishmaniasis caused by Leishmania donovani in three patients co-infected with visceral leishmaniasis and human immunodeficiency virus/acquired immunodeficiency syndrome in Ethiopia.

Authors:  Tesfaye Gelanew; Zewdu Hurissa; Ermias Diro; Aysheshm Kassahun; Katrin Kuhls; Gabriele Schönian; Asrat Hailu
Journal:  Am J Trop Med Hyg       Date:  2011-06       Impact factor: 2.345

2.  Nested PCR assay for detection of Leishmania donovani in slit aspirates from post-kala-azar dermal Leishmaniasis Lesions.

Authors:  Gannavaram Sreenivas; N A Ansari; Joginder Kataria; Poonam Salotra
Journal:  J Clin Microbiol       Date:  2004-04       Impact factor: 5.948

Review 3.  The relationship between leishmaniasis and AIDS: the second 10 years.

Authors:  Jorge Alvar; Pilar Aparicio; Abraham Aseffa; Margriet Den Boer; Carmen Cañavate; Jean-Pierre Dedet; Luigi Gradoni; Rachel Ter Horst; Rogelio López-Vélez; Javier Moreno
Journal:  Clin Microbiol Rev       Date:  2008-04       Impact factor: 26.132

4.  Parasite detection in patients with post kala-azar dermal leishmaniasis in India: a comparison between molecular and immunological methods.

Authors:  P Salotra; G Sreenivas; K R Beena; A Mukherjee; V Ramesh
Journal:  J Clin Pathol       Date:  2003-11       Impact factor: 3.411

Review 5.  PKDL and other dermal lesions in HIV co-infected patients with Leishmaniasis: review of clinical presentation in relation to immune responses.

Authors:  Eduard E Zijlstra
Journal:  PLoS Negl Trop Dis       Date:  2014-11-20

6.  Case study of a patient with HIV-AIDS and visceral leishmaniasis co-infection in multiple episodes.

Authors:  Elis Dionísio da Silva; Luiz Dias de Andrade; Paulo Sérgio Ramos de Araújo; Vera Magalhães Silveira; Carlos Eduardo Padilha; Maria Almerice Lopes da Silva; Zulma Maria de Medeiros
Journal:  Rev Inst Med Trop Sao Paulo       Date:  2013 Nov-Dec       Impact factor: 1.846

  6 in total

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