Literature DB >> 12571053

Aminopeptidase C of Aspergillus niger is a novel phenylalanine aminopeptidase.

Daniëlle E J W Basten1, Peter J T Dekker, Peter J Schaap.   

Abstract

A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share similarity with some mammalian acyl-peptide hydrolase sequences. ApsC was found to be most active towards phenylalanine beta-naphthylamide (F-beta NA) and phenylalanine para-nitroanilide (F-pNA), but it also displayed activity towards other amino acids with aromatic side chains coupled to beta NA; other amino acids with non-aromatic side chains coupled to either pNA or beta NA were not hydrolyzed or were poorly hydrolyzed. ApsC was not able to hydrolyze N-acetylalanine-pNA, a substrate for acyl-peptide hydrolases.

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Year:  2003        PMID： 12571053      PMCID： PMC143615          DOI： 10.1128/AEM.69.2.1246-1250.2003

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  22 in total

1.  Structural relationship between lipases and peptidases of the prolyl oligopeptidase family.

Authors:  L Polgár
Journal:  FEBS Lett       Date:  1992-10-26       Impact factor: 4.124

2.  The genetics of Aspergillus nidulans.

Authors:  G PONTECORVO; J A ROPER; L M HEMMONS; K D MACDONALD; A W J BUFTON
Journal:  Adv Genet       Date:  1953       Impact factor: 1.944

3.  In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis.

Authors:  J Rosenfeld; J Capdevielle; J C Guillemot; P Ferrara
Journal:  Anal Biochem       Date:  1992-05-15       Impact factor: 3.365

4.  Fluorescence reaction for amino acids.

Authors:  M Roth
Journal:  Anal Chem       Date:  1971-06       Impact factor: 6.986

5.  Purification and characterization of two serine carboxypeptidases from Aspergillus niger and their use in C-terminal sequencing of proteins and peptide synthesis.

Authors:  F Dal Degan; B Ribadeau-Dumas; K Breddam
Journal:  Appl Environ Microbiol       Date:  1992-07       Impact factor: 4.792

6.  Tryptophan auxotrophic mutants in Aspergillus niger: inactivation of the trpC gene by cotransformation mutagenesis.

Authors:  T Goosen; F van Engelenburg; F Debets; K Swart; K Bos; H van den Broek
Journal:  Mol Gen Genet       Date:  1989-10

7.  Lysine aminopeptidase of Aspergillus niger.

Authors:  Daniëlle E J W Basten; Jaap Visser; Peter J Schaap
Journal:  Microbiology       Date:  2001-08       Impact factor: 2.777

8.  Structure of the Aspergillus niger pelA gene and its expression in Aspergillus niger and Aspergillus nidulans.

Authors:  M A Kusters-van Someren; J A Harmsen; H C Kester; J Visser
Journal:  Curr Genet       Date:  1991-09       Impact factor: 3.886

9.  External and internal forms of yeast aminopeptidase II.

Authors:  J Frey; K H Röhm
Journal:  Eur J Biochem       Date:  1979-06

10.  Proteolysis in eucaryotic cells: aminopeptidases and dipeptidyl aminopeptidases of yeast revisited.

Authors:  T Achstetter; C Ehmann; D H Wolf
Journal:  Arch Biochem Biophys       Date:  1983-10-01       Impact factor: 4.013
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  6 in total

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Authors:  Daniëlle E J W Basten; Antoine P H A Moers; Albert J J van Ooyen; Peter J Schaap
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2.  Draft Genome Sequence of Lentilactobacillus kosonis NBRC 111893, Isolated from a Japanese Sugar-Vegetable Fermented Beverage called Kôso.

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3.  Characterization of a multimeric, eukaryotic prolyl aminopeptidase: an inducible and highly specific intracellular peptidase from the non-pathogenic fungus Talaromyces emersonii.

Authors:  Cathal S Mahon; Anthony J O'Donoghue; David H Goetz; Patrick G Murray; Charles S Craik; Maria G Tuohy
Journal:  Microbiology (Reading)       Date:  2009-06-25       Impact factor: 2.777

4.  Debittering of Protein Hydrolysates by Lactobacillus LBL-4 Aminopeptidase.

Authors:  Bozhidar Tchorbanov; Margarita Marinova; Lydia Grozeva
Journal:  Enzyme Res       Date:  2011-08-24

5.  Bioinformatic mapping of a more precise Aspergillus niger degradome.

Authors:  Zixing Dong; Shuangshuang Yang; Byong H Lee
Journal:  Sci Rep       Date:  2021-01-12       Impact factor: 4.379

6.  Functional expression and characterization of a novel aminopeptidase B from Aspergillus niger in Pichia pastoris.

Authors:  Peng Song; Wei Feng
Journal:  3 Biotech       Date:  2021-07-06       Impact factor: 2.893
  6 in total

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