Literature DB >> 12568584

Converting the sacrificial DNA repair protein N-ada into a catalytic methyl phosphotriester repair enzyme.

Chuan He1, Hua Wei, Gregory L Verdine.   

Abstract

Mutation of the active-site residue Cys38 of N-Ada converts it from a sacrificial DNA repair protein to an enzyme that uses methanethiol as an external sacrificial reagent to repair DNA methyl phosphotriesters catalytically.

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Year:  2003        PMID： 12568584     DOI： 10.1021/ja028046a

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  4 in total

Review 1.  Direct reversal of DNA alkylation damage.

Authors:  Yukiko Mishina; Erica M Duguid; Chuan He
Journal:  Chem Rev       Date:  2006-02       Impact factor: 60.622

Review 2.  The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species.

Authors:  Monika Schmoll; Christoph Dattenböck; Nohemí Carreras-Villaseñor; Artemio Mendoza-Mendoza; Doris Tisch; Mario Ivan Alemán; Scott E Baker; Christopher Brown; Mayte Guadalupe Cervantes-Badillo; José Cetz-Chel; Gema Rosa Cristobal-Mondragon; Luis Delaye; Edgardo Ulises Esquivel-Naranjo; Alexa Frischmann; Jose de Jesus Gallardo-Negrete; Monica García-Esquivel; Elida Yazmin Gomez-Rodriguez; David R Greenwood; Miguel Hernández-Oñate; Joanna S Kruszewska; Robert Lawry; Hector M Mora-Montes; Tania Muñoz-Centeno; Maria Fernanda Nieto-Jacobo; Guillermo Nogueira Lopez; Vianey Olmedo-Monfil; Macario Osorio-Concepcion; Sebastian Piłsyk; Kyle R Pomraning; Aroa Rodriguez-Iglesias; Maria Teresa Rosales-Saavedra; J Alejandro Sánchez-Arreguín; Verena Seidl-Seiboth; Alison Stewart; Edith Elena Uresti-Rivera; Chih-Li Wang; Ting-Fang Wang; Susanne Zeilinger; Sergio Casas-Flores; Alfredo Herrera-Estrella
Journal:  Microbiol Mol Biol Rev       Date:  2016-02-10       Impact factor: 11.056

3.  The solution structure of the methylated form of the N-terminal 16-kDa domain of Escherichia coli Ada protein.

Authors:  Hiroto Takinowaki; Yasuhiro Matsuda; Takuya Yoshida; Yuji Kobayashi; Tadayasu Ohkubo
Journal:  Protein Sci       Date:  2006-02-01       Impact factor: 6.725

4.  The Escherichia coli alkylation response protein AidB is a redox partner of flavodoxin and binds RNA and acyl carrier protein.

Authors:  Scott B Mulrooney; Michael J Howard; Robert P Hausinger
Journal:  Arch Biochem Biophys       Date:  2011-07-18       Impact factor: 4.013
  4 in total

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