Literature DB >> 12567338

Delivery rate accuracy of portable, bolus-capable infusion pumps used for patient-controlled continuous regional analgesia.

Brian M Ilfeld1, Timothy E Morey, F Kayser Enneking.   

Abstract

BACKGROUND AND OBJECTIVES: Portable patient-controlled pumps used for perineural local anesthetic infusion appear to be gaining acceptance and are used for an increasing number of medically unsupervised ambulatory patients. The infusion rate accuracy and reliability of these pumps, which allow patient-controlled boluses of potentially toxic medication, has not been independently investigated. We performed this laboratory study to define the flow-rate accuracy, reliability, and profiles of various portable bolus-capable infusion pumps and varied several factors that may influence pump performance.
METHODS: Using a computer/scale combination, 4 electronic pumps were tested with 1 and 2 sets of batteries over 100 hours. One elastomeric pump was tested with its flow-regulator at room temperature (20 degrees C to 24 degrees C), skin temperature (32 degrees C), and increased temperature (36 degrees C). The elastomeric pump was also tested by varying the height of the pump relative to the distal end of the catheter.
RESULTS: Infusion rate accuracy differed significantly among the pumps, exhibiting flow rates within +/-15% of their expected rate for 29% to 100% of their infusion duration. Changing the batteries after 50 hours affected the profile of 1 of the 4 electronic pumps. For the elastomeric pump, an increase in temperature significantly increased the infusion rate. An increase or decrease in pump-to-scale height significantly increased or decreased the infusion rate, respectively.
CONCLUSIONS: These results suggest that factors such as flow-rate accuracy and consistency, infusion profile, and temperature sensitivity should be taken into consideration when choosing a portable infusion pump for local anesthetic administration.

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Year:  2003        PMID: 12567338     DOI: 10.1053/rapm.2003.50008

Source DB:  PubMed          Journal:  Reg Anesth Pain Med        ISSN: 1098-7339            Impact factor:   6.288


  7 in total

1.  Ultrasound-guided (needle-in-plane) perineural catheter insertion: the effect of catheter-insertion distance on postoperative analgesia.

Authors:  Brian M Ilfeld; Navparkash S Sandhu; Vanessa J Loland; Sarah J Madison; Preetham J Suresh; Edward R Mariano; Michael L Bishop; Alexandra K Schwartz; Daniel K Lee
Journal:  Reg Anesth Pain Med       Date:  2011 May-Jun       Impact factor: 6.288

2.  Cost-effectiveness analysis of levobupivacaine 0.5 %, a local anesthetic, infusion in the surgical wound after modified radical mastectomy.

Authors:  Lourdes Ferreira Laso; Amanda López Picado; Fernando Antoñanzas Villar; Laura Lamata de la Orden; Mar Ceballos Garcia; Carolina Ibañez López; Lorena Pipaon Ruilope; Felix Lamata Hernandez; Cesar Valero Martinez; Felipe Aizpuru; Roberto Hernandez Chaves
Journal:  Clin Drug Investig       Date:  2015-09       Impact factor: 2.859

Review 3.  Upper extremity regional anesthesia: essentials of our current understanding, 2008.

Authors:  Joseph M Neal; J C Gerancher; James R Hebl; Brian M Ilfeld; Colin J L McCartney; Carlo D Franco; Quinn H Hogan
Journal:  Reg Anesth Pain Med       Date:  2009 Mar-Apr       Impact factor: 6.288

4.  A randomized, triple-masked, active-controlled investigation of the relative effects of dose, concentration, and infusion rate for continuous popliteal-sciatic nerve blocks in volunteers.

Authors:  S J Madison; A M Monahan; R R Agarwal; T J Furnish; E J Mascha; Z Xu; M C Donohue; A C Morgan; B M Ilfeld
Journal:  Br J Anaesth       Date:  2014-09-23       Impact factor: 9.166

5.  Local anaesthetic infusion with elastomeric pump after arthroscopic subacromial decompression.

Authors:  Kevin Little; Anand Pillai; Umberto Fazzi; Neil Storey
Journal:  Ann R Coll Surg Engl       Date:  2007-05       Impact factor: 1.891

Review 6.  Newer drug delivery systems in anesthesia.

Authors:  Sona Dave; Deepa Shriyan; Pinakin Gujjar
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2017 Apr-Jun

7.  The flow Rate Accuracy of Elastomeric Infusion Pumps After Repeated Filling.

Authors:  Masood Mohseni; Amin Ebneshahidi
Journal:  Anesth Pain Med       Date:  2014-04-07
  7 in total

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