Literature DB >> 12567286

The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare.

Sanae El Bardai, Nicole Morel, Maurice Wibo, Nicolas Fabre, Gabriel Llabres, Badiaa Lyoussi, Joëlle Quetin-Leclercq.   

Abstract

Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin as the most active compounds.

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Year:  2003        PMID： 12567286     DOI： 10.1055/s-2003-37042

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  13 in total

1.  Characterisation of marrubenol, a diterpene extracted from Marrubium vulgare, as an L-type calcium channel blocker.

Authors:  Sanae El-Bardai; Maurice Wibo; Marie-Christine Hamaide; Badiaa Lyoussi; Joelle Quetin-Leclercq; Nicole Morel
Journal:  Br J Pharmacol       Date:  2003-11-03       Impact factor: 8.739

2.  Chromatographic Fingerprint Analysis of Marrubiin in Marrubium vulgare L. via HPTLC Technique.

Authors:  Keyvan Yousefi; Sanaz Hamedeyazdan; Mohammadali Torbati; Fatemeh Fathiazad
Journal:  Adv Pharm Bull       Date:  2016-03-17

3.  The in-vitro evaluation of antibacterial, antifungal and cytotoxic properties of Marrubium vulgare L. essential oil grown in Tunisia.

Authors:  Zied Zarai; Adel Kadri; Ines Ben Chobba; Riadh Ben Mansour; Ahmed Bekir; Hafedh Mejdoub; Néji Gharsallah
Journal:  Lipids Health Dis       Date:  2011-09-21       Impact factor: 3.876

Review 4.  Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II.

Authors:  M Akhtar Anwar; Sara S Al Disi; Ali H Eid
Journal:  Front Pharmacol       Date:  2016-03-08       Impact factor: 5.810

Review 5.  Marrubium vulgare L.: A Phytochemical and Pharmacological Overview.

Authors:  Milica Aćimović; Katarina Jeremić; Nebojša Salaj; Neda Gavarić; Biljana Kiprovski; Vladimir Sikora; Tijana Zeremski
Journal:  Molecules       Date:  2020-06-24       Impact factor: 4.411

6.  Marrubium vulgare L. Leave Extract: Phytochemical Composition, Antioxidant and Wound Healing Properties.

Authors:  Bédis Amri; Emanuela Martino; Francesca Vitulo; Federica Corana; Leila Bettaieb-Ben Kaâb; Marta Rui; Daniela Rossi; Michela Mori; Silvia Rossi; Simona Collina
Journal:  Molecules       Date:  2017-10-28       Impact factor: 4.411

Review 7.  Natural Antispasmodics: Source, Stereochemical Configuration, and Biological Activity.

Authors:  Edith Fabiola Martínez-Pérez; Zaida N Juárez; Luis R Hernández; Horacio Bach
Journal:  Biomed Res Int       Date:  2018-10-08       Impact factor: 3.411

8.  Intensification of marrubiin concentration by optimization of microwave-assisted (low CO2 yielding) extraction process for Marrubium vulgare using central composite design and antioxidant evaluation.

Authors:  Vineet Mittal; Arun Nanda
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

9.  Spray Drying of a Subcritical Extract Using Marrubium vulgare as a Method of Choice for Obtaining High Quality Powder.

Authors:  Aleksandra Gavarić; Jelena Vladić; Rita Ambrus; Stela Jokić; Piroska Szabó-Révész; Milan Tomić; Marijana Blažić; Senka Vidović
Journal:  Pharmaceutics       Date:  2019-10-11       Impact factor: 6.321

10.  Total Syntheses of Marrubiin and Related Labdane Diterpene Lactones.

Authors:  Yukari Sakagami; Naoki Kondo; Yuki Sawayama; Hiroyuki Yamakoshi; Seiichi Nakamura
Journal:  Molecules       Date:  2020-04-01       Impact factor: 4.411
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