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Literature DB >> 1256442

Mode of action of the antitumor compound bruceantin, an inhibitor of protein synthesis.

L L Liao, S M Kupchan, S B Horwitz.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 1976 PMID： 1256442

Source DB: PubMed Journal: Mol Pharmacol ISSN： 0026-895X Impact factor: 4.436

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24 in total

1. Antitumor Agents. 282. 2'-(R)-O-acetylglaucarubinone, a quassinoid from Odyendyea gabonensis as a potential anti-breast and anti-ovarian cancer agent.

Authors: Yoshihide Usami; Kyoko Nakagawa-Goto; Jing-Yu Lang; Yoon Kim; Chin-Yu Lai; Masuo Goto; Nobuko Sakurai; Masahiko Taniguchi; Toshiyuki Akiyama; Susan L Morris-Natschke; Kenneth F Bastow; Gordon Cragg; David J Newman; Mihoyo Fujitake; Koichi Takeya; Mien-Chie Hung; Eva Y-H P Lee; Kuo-Hsiung Lee
Journal: J Nat Prod Date: 2010-09-24 Impact factor: 4.050

2. Bruceantin inhibits multiple myeloma cancer stem cell proliferation.

Authors: Mark E Issa; Sarah Berndt; Gilles Carpentier; John M Pezzuto; Muriel Cuendet
Journal: Cancer Biol Ther Date: 2016-07-19 Impact factor: 4.742

3. Effect of helenalin and bis(helenalinyl)malonate on nucleic acid and protein synthesis in human KB carcinoma cells.

Authors: I H Hall; A A Grippo; K H Lee; S G Chaney; D J Holbrook
Journal: Pharm Res Date: 1987-12 Impact factor: 4.200

4. Brusatol overcomes chemoresistance through inhibition of protein translation.

Authors: Bryan Harder; Wang Tian; James J La Clair; Aik-Choon Tan; Aikseng Ooi; Eli Chapman; Donna D Zhang
Journal: Mol Carcinog Date: 2017-02-08 Impact factor: 4.784

5. Bruceantin, a potent amoebicide from a plant, Brucea antidysenterica.

Authors: F D Gillin; D S Reiner; M Suffness
Journal: Antimicrob Agents Chemother Date: 1982-08 Impact factor: 5.191

6. Growth inhibitory, insecticidal and antifeedant effects of some antileukemic and cytotoxic quassinoids on two species of agricultural pests.

Authors: J A Klocke; M Arisawa; S S Handa; A D Kinghorn; G A Cordell; N R Farnsworth
Journal: Experientia Date: 1985-03-15

Mode of action of the antitumor compound bruceantin, an inhibitor of protein synthesis.

1. Antitumor Agents. 282. 2'-(R)-O-acetylglaucarubinone, a quassinoid from Odyendyea gabonensis as a potential anti-breast and anti-ovarian cancer agent.

2. Bruceantin inhibits multiple myeloma cancer stem cell proliferation.

3. Effect of helenalin and bis(helenalinyl)malonate on nucleic acid and protein synthesis in human KB carcinoma cells.

4. Brusatol overcomes chemoresistance through inhibition of protein translation.

5. Bruceantin, a potent amoebicide from a plant, Brucea antidysenterica.

6. Growth inhibitory, insecticidal and antifeedant effects of some antileukemic and cytotoxic quassinoids on two species of agricultural pests.

7. Antitumor activity and mechanism of action of the marine compound girodazole.

8. A Phase II study of Bruceantin (NSC-165, 563) in advanced malignant melanoma.

9. Clinical pharmacology of bruceantin by radioimmunoassay.

10. The effects of boron containing peptides on L1210 lymphoid leukemia metabolism.