Literature DB >> 12558468

The burden of age-related macular degeneration: results of a cohort study in two French referral centres.

Julia Bonastre1, Claude Le Pen, Gisèle Soubrane, Gabriel Quentel.   

Abstract

OBJECTIVE: To describe the economic impact of age-related macular degeneration (AMD) and to assess its medical and non-medical costs. DESIGN AND SETTINGS: An observational study was carried out in 105 patients in two French centres in a sample of 105 French patients. All consecutive patients, consulting during a 3-week period, were included provided they were 60 years of age or older and they presented an exudative form of AMD with a distant visual acuity in the best eye < or = 20/40. Data collected included clinical items, treatment modalities, medical follow-up, transport costs, impact of AMD on living conditions and welfare payments related to visual impairment. Costs were presented in 2000 values. PERSPECTIVE: General payer perspective (Social Security, private health insurance and patient).
RESULTS: Mean age was 79.3 years and ranged from 62.8-95 years. Average length of disease evolution was 3.5 years. During a 3-month period, patients had a mean of 2.6 visits to the ophthalmologist. Thirty percent of the patients used vascular medications and 72.4% had been previously treated by laser photocoagulation. Only 10% had benefited from visual rehabilitation. Annual AMD cost per patient was 3660.29 euros (EUR) [95% CI: 2881.92-4438.62]. Half of these annual costs were medical costs. Other major cost components were home help costs EUR904.91 [95% CI: 478.88-1330.94] and transport costs for care EUR542.73 [95% CI: 146.31-939.14]. Non-medical costs were significantly higher for patients with more severe disease.
CONCLUSIONS: The economic argument that costs are higher in patients with the lowest visual acuity emphasises the necessity of early detection and treatment of patients with AMD.

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Mesh:

Year:  2003        PMID: 12558468     DOI: 10.2165/00019053-200321030-00003

Source DB:  PubMed          Journal:  Pharmacoeconomics        ISSN: 1170-7690            Impact factor:   4.981


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  22 in total

1.  Age-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions.

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2.  [Evaluation of the German version of the caregiver reaction assessment questionnaire for informal caregivers of patients with neovascular age-related macular degeneration].

Authors:  H Weyer-Wendl; M Tamm; P Walter
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Authors:  Kathleen M Ke; Usha Chakravarthy; Ciaran O'Neill
Journal:  Drugs Aging       Date:  2006       Impact factor: 3.923

Review 4.  Cost-of-illness studies : a review of current methods.

Authors:  Ebere Akobundu; Jing Ju; Lisa Blatt; C Daniel Mullins
Journal:  Pharmacoeconomics       Date:  2006       Impact factor: 4.981

5.  How much is the cost of visual impairment: caveat emptor.

Authors:  Catherine Meads; Chris Hyde
Journal:  Pharmacoeconomics       Date:  2006       Impact factor: 4.981

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Review 7.  [Cost of illness of age-related macular degeneration. Systematic review on the development of a costs diary].

Authors:  J Gibbert; D Müller; S Fauser; S Stock
Journal:  Ophthalmologe       Date:  2013-06       Impact factor: 1.059

8.  Health resource utilization and the economic burden of patients with wet age-related macular degeneration in Thailand.

Authors:  Piyameth Dilokthornsakul; Nathorn Chaiyakunapruk; Paisan Ruamviboonsuk; Mansing Ratanasukon; Somsanguan Ausayakhun; Akrapope Tungsomeroengwong; Nattapol Pokawattana; Chalakorn Chanatittarat
Journal:  Int J Ophthalmol       Date:  2014-02-18       Impact factor: 1.779

9.  Patient characteristics and treatment of neovascular age-related macular degeneration in France: the LUEUR1 observational study.

Authors:  Salomon-Yves Cohen; Eric H Souied; Michel Weber; Gérard Dupeyron; Gérard de Pouvourville; Michel Lievre; Anne Ponthieux
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2010-11-06       Impact factor: 3.117

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Authors:  Pamela A Weber; Barbara M Wirostko; Xiao Xu; Thomas F Goss; Gergana Zlateva
Journal:  BMC Ophthalmol       Date:  2010-02-09       Impact factor: 2.209

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