Literature DB >> 12558062

5,9,23-Triacontatrienoic methyl ester, an elastase inhibitor from the marine sponge Chondrilla nucula.

Michèle Meyer1, Michèle Guyot.   

Abstract

A polyethylenic fatty ester was isolated from the marine sponge Chondrilla nucula. The structure was elucidated through NMR spectral data and MS analysis as 5,9,23-triacontatrienoic methyl ester 1. Compound 1 is an elastase inhibitor [ID50 = 10 microg/mL (2 x 10(-5) M)].

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Year:  2002        PMID： 12558062     DOI： 10.1007/s11745-002-1007-y

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  14 in total

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Authors:  D Sklan; R Rappaport; M Vered
Journal:  Lung       Date:  1990       Impact factor: 2.584

Review 2.  Synthetic inhibitors of elastase.

Authors:  P D Edwards; P R Bernstein
Journal:  Med Res Rev       Date:  1994-03       Impact factor: 12.944

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Journal:  Annu Rev Med       Date:  1985       Impact factor: 13.739

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Journal:  Justus Liebigs Ann Chem       Date:  1966-11

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Authors:  A Janoff
Journal:  Am Rev Respir Dis       Date:  1985-08

6.  The occurrence of two new prostaglandin derivatives (15-epi-PGA2 and its acetate, methyl ester) in the gorgonian Plexaura homomalla chemistry of coelenterates. XV.

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Journal:  Tetrahedron Lett       Date:  1969-12       Impact factor: 2.415

7.  Proteinase/proteinase inhibitor imbalance in sputum sol phases from patients with chronic obstructive pulmonary disease. Suggestions for a key role played by antileukoprotease.

Authors:  P D Piccioni; J A Kramps; A Rudolphus; A Bulgheroni; M Luisetti
Journal:  Chest       Date:  1992-11       Impact factor: 9.410

8.  New unsaturated long-chain fatty acids in the phospholipids from the Axinellida sponges Trikentrion loeve and Pseudaxinella cf. lunaecharta.

Authors:  G Barnathan; J M Kornprobst; P Doumenq; J Miralles
Journal:  Lipids       Date:  1996-02       Impact factor: 1.880

9.  On the isolation of 2-hydroxydocosanoic and 2-hydroxytricosanoic acids from the marine sponge Amphimedon compressa.

Authors:  N M Carballeira; M R Lopez
Journal:  Lipids       Date:  1989-01       Impact factor: 1.880

10.  Phospholipid studies of marine organisms: V(1) new α-methoxy acids fromHigginsia tethyoides.

Authors:  E Ayanoglu; S Popov; J M Kornprobst; A Aboud-Bichara; C Djerassi
Journal:  Lipids       Date:  1983-11       Impact factor: 1.880
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  1 in total

1.  Trans and positional ethylenic bonds in two dominant isomers of eicosapentaenoic acid from the freshwater sponge Baicalospongia bacillifera.

Authors:  Andrey B Imbs; Svetlana A Rodkina
Journal:  Lipids       Date:  2005-09       Impact factor: 1.880
  1 in total

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