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Literature DB >> 12554905

Multiple roles of nitric oxide in the airways.

Abstract

Nitric oxide is endogenously released in the airways by nitric oxide synthase. Functionally, two isoforms of this enzyme exist: constitutive and inducible. The former seems to protect airways from excessive bronchoconstriction while the latter has a modulatory role in inflammatory disorders of the airways such as asthma. This review explores the physiological and pathophysiological role of endogenous nitric oxide in the airways, and the clinical aspects of monitoring nitric oxide in exhaled air of patients with respiratory disease.

Entities: Chemical Disease Species

Mesh：

Substances：
Biomarkers
Nitric Oxide

Year: 2003 PMID： 12554905 PMCID： PMC1746564 DOI： 10.1136/thorax.58.2.175

Source DB: PubMed Journal: Thorax ISSN： 0040-6376 Impact factor: 9.139

141 in total

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Journal: Neurosci Lett Date: 1993-01-12 Impact factor: 3.046

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Authors: A W Taylor-Robinson; R S Phillips; A Severn; S Moncada; F Y Liew
Journal: Science Date: 1993-06-25 Impact factor: 47.728

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Journal: Eur Respir J Date: 1993-02 Impact factor: 16.671

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Authors: S Archer
Journal: FASEB J Date: 1993-02-01 Impact factor: 5.191

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Journal: J Clin Invest Date: 1993-08 Impact factor: 14.808

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Journal: Br J Pharmacol Date: 1993-01 Impact factor: 8.739

88 in total

Review 1. Oxidants and asthma.

Authors: G Caramori; A Papi
Journal: Thorax Date: 2004-02 Impact factor: 9.139

2. Acute effect of cigarette smoke and nicotine on airway blood flow and airflow in healthy smokers.

Authors: Kanwaldeep Randhawa; Eliana Mendes; Adam Wanner
Journal: Lung Date: 2006-11-16 Impact factor: 2.584

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Authors: William S Linn; Marisela Avila; Henry Gong
Journal: Arch Environ Health Date: 2004-08

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Authors: V M D Struben; M H Wieringa; C J Mantingh; J C de Jongste; L Feenstra
Journal: Eur Arch Otorhinolaryngol Date: 2006-05-19 Impact factor: 2.503

5. Airway hyperresponsiveness in allergically inflamed mice: the role of airway closure.

Authors: Lennart K A Lundblad; John Thompson-Figueroa; Gilman B Allen; Lisa Rinaldi; Ryan J Norton; Charles G Irvin; Jason H T Bates
Journal: Am J Respir Crit Care Med Date: 2007-01-25 Impact factor: 21.405

6. Increased alveolar nitric oxide concentration and high levels of leukotriene B(4) and 8-isoprostane in exhaled breath condensate in patients with asbestosis.

Authors: Hannele Lehtonen; Panu Oksa; Lauri Lehtimäki; Anna Sepponen; Riina Nieminen; Hannu Kankaanranta; Seppo Saarelainen; Ritva Järvenpää; Jukka Uitti; Eeva Moilanen
Journal: Thorax Date: 2007-01-24 Impact factor: 9.139

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Authors: Eugenia Mata-Greenwood; Dong-Bao Chen
Journal: Reprod Sci Date: 2008-01 Impact factor: 3.060

Review 8. Targeted Therapy for Severe Asthma: Identifying the Right Patients.

Authors: Kathy Low; Philip G Bardin
Journal: Mol Diagn Ther Date: 2017-06 Impact factor: 4.074

9. Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components.

Authors: Robert J Lee; Bei Chen; Kevin M Redding; Robert F Margolskee; Noam A Cohen
Journal: Innate Immun Date: 2013-09-17 Impact factor: 2.680

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Authors: Rohit Katial; Lora Stewart
Journal: Curr Allergy Asthma Rep Date: 2007-11 Impact factor: 4.806