Literature DB >> 8100366

The role of TH1 and TH2 cells in a rodent malaria infection.

A W Taylor-Robinson1, R S Phillips, A Severn, S Moncada, F Y Liew.   

Abstract

CD4+ T cells play a major role in protective immunity against the blood stage of malaria, but the mechanism of protection is unclear. By adoptive transfer of cloned T cell lines, direct evidence is provided that both TH1 and TH2 subsets of CD4+ T cells can protect mice against Plasmodium chabaudi chabaudi infection. TH1 cells protect by a nitric oxide-dependent mechanism, whereas TH2 cells protect by the enhancement and accelerated production of specific immunoglobulin G1 antibody.

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Year:  1993        PMID： 8100366     DOI： 10.1126/science.8100366

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  87 in total

Review 1.  Pathophysiological mechanisms of asthma. Application of cell and molecular biology techniques.

Authors:  K F Chung; I M Adcock
Journal:  Mol Biotechnol       Date:  2001-07       Impact factor: 2.695

2.  The purine salvage enzyme hypoxanthine guanine xanthine phosphoribosyl transferase is a major target antigen for cell-mediated immunity to malaria.

Authors:  Morris O Makobongo; George Riding; Huji Xu; Chakrit Hirunpetcharat; Dianne Keough; John de Jersey; Peter Willadsen; Michael F Good
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-19       Impact factor: 11.205

3.  Nitric oxide preferentially induces type 1 T cell differentiation by selectively up-regulating IL-12 receptor beta 2 expression via cGMP.

Authors:  Wanda Niedbala; Xiao-Qing Wei; Carol Campbell; Duncan Thomson; Mousa Komai-Koma; Foo Y Liew
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-25       Impact factor: 11.205

4.  Nature and specificity of the required protective immune response that develops postchallenge in mice vaccinated with the 19-kilodalton fragment of Plasmodium yoelii merozoite surface protein 1.

Authors:  Jiraprapa Wipasa; Huji Xu; Morris Makobongo; Michelle Gatton; Anthony Stowers; Michael F Good
Journal:  Infect Immun       Date:  2002-11       Impact factor: 3.441

5.  Gamma interferon production is critical for protective immunity to infection with blood-stage Plasmodium berghei XAT but neither NO production nor NK cell activation is critical.

Authors:  T Yoneto; T Yoshimoto; C R Wang; Y Takahama; M Tsuji; S Waki; H Nariuchi
Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

6.  Immune responses of NIH mice infected with avirulent and virulent strains of Plasmodium chabaudi adami single and mixed infections.

Authors:  M J Namazi; R S Phillips
Journal:  Korean J Parasitol       Date:  2010-03-18       Impact factor: 1.341

7.  A Plasmodium-encoded cytokine suppresses T-cell immunity during malaria.

Authors:  Tiffany Sun; Thomas Holowka; Yan Song; Swen Zierow; Lin Leng; Yibang Chen; Huabao Xiong; Jason Griffith; Mehdi Nouraie; Philip E Thuma; Elias Lolis; Chris J Janse; Victor R Gordeuk; Kevin Augustijn; Richard Bucala
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-09       Impact factor: 11.205

8.  Stimulation of nitric oxide production in macrophages by Babesia bovis.

Authors:  R W Stich; L K Shoda; M Dreewes; B Adler; T W Jungi; W C Brown
Journal:  Infect Immun       Date:  1998-09       Impact factor: 3.441

9.  B cells are required for the switch from Th1- to Th2-regulated immune responses to Plasmodium chabaudi chabaudi infection.

Authors:  A W Taylor-Robinson; R S Phillips
Journal:  Infect Immun       Date:  1994-06       Impact factor: 3.441

10.  Immunization of cattle with recombinant Babesia bovis merozoite surface antigen-1.

Authors:  S A Hines; G H Palmer; D P Jasmer; W L Goff; T F McElwain
Journal:  Infect Immun       Date:  1995-01       Impact factor: 3.441
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