Literature DB >> 12549675

Reactant- and product-based approaches to the design of combinatorial libraries.

Valerie J Gillet1.   

Abstract

Mesh:

Year:  2002        PMID: 12549675     DOI: 10.1023/a:1021324225524

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


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  11 in total

1.  Computational methods for the prediction of 'drug-likeness'

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Journal:  Drug Discov Today       Date:  2000-02       Impact factor: 7.851

2.  Enhancing the hit-to-lead properties of lead optimization libraries

Authors: 
Journal:  J Chem Inf Comput Sci       Date:  2000-03

3.  Combinatorial library design: maximizing model-fitting compounds within matrix synthesis constraints

Authors: 
Journal:  J Chem Inf Comput Sci       Date:  2000-05

4.  Designing targeted libraries with genetic algorithms.

Authors:  R P Sheridan; S G SanFeliciano; S K Kearsley
Journal:  J Mol Graph Model       Date:  2000 Aug-Oct       Impact factor: 2.518

5.  Is there a difference between leads and drugs? A historical perspective.

Authors:  T I Oprea; A M Davis; S J Teague; P D Leeson
Journal:  J Chem Inf Comput Sci       Date:  2001 Sep-Oct

6.  A scoring scheme for discriminating between drugs and nondrugs.

Authors:  J Sadowski; H Kubinyi
Journal:  J Med Chem       Date:  1998-08-27       Impact factor: 7.446

7.  Can we learn to distinguish between "drug-like" and "nondrug-like" molecules?

Authors:  A Ajay; W P Walters; M A Murcko
Journal:  J Med Chem       Date:  1998-08-27       Impact factor: 7.446

8.  Rational combinatorial library design. 1. Focus-2D: a new approach to the design of targeted combinatorial chemical libraries.

Authors:  W Zheng; S J Cho; A Tropsha
Journal:  J Chem Inf Comput Sci       Date:  1998 Mar-Apr

9.  Identification of biological activity profiles using substructural analysis and genetic algorithms.

Authors:  V J Gillet; P Willett; J Bradshaw
Journal:  J Chem Inf Comput Sci       Date:  1998 Mar-Apr

10.  Rational combinatorial library design. 2. Rational design of targeted combinatorial peptide libraries using chemical similarity probe and the inverse QSAR approaches.

Authors:  S J Cho; W Zheng; A Tropsha
Journal:  J Chem Inf Comput Sci       Date:  1998 Mar-Apr
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