Literature DB >> 12548582

The biology of breast carcinoma.

Judith Clancy Keen1, Nancy E Davidson.   

Abstract

The biology of breast carcinoma is complex, with multiple factors contributing to its development and progression. The current review focuses on the role of several critical genes including estrogen receptor, progesterone receptor, retinoic acid receptor-beta, epidermal growth factor receptor family members, p53, BRCA1, and BRCA2 as risk factors for the development of disease, predictors of prognosis and response to therapy, and as therapeutic targets. Studies of the biology of these and other genes that contribute to the development and progression of breast carcinoma have had and will continue to have great impact on all aspects of disease management. Copyright 2003 American Cancer Society.DOI 10.1002/cncr.11126

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Year:  2003        PMID： 12548582     DOI： 10.1002/cncr.11126

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  59 in total

Review 1.  Interrogating mouse mammary cancer models: insights from gene expression profiling.

Authors:  Antonio A Fargiano; Kartiki V Desai; Jeffrey E Green
Journal:  J Mammary Gland Biol Neoplasia       Date:  2003-07       Impact factor: 2.673

2.  Predictive markers in elderly patients with estrogen receptor-positive breast cancer treated with aromatase inhibitors: an array-based pharmacogenetic study.

Authors:  E Rumiato; A Brunello; S Ahcene-Djaballah; L Borgato; M Gusella; D Menon; F Pasini; A Amadori; D Saggioro; V Zagonel
Journal:  Pharmacogenomics J       Date:  2015-10-27       Impact factor: 3.550

3.  Molecular characterization of a human BRCA2 homolog in Leishmania donovani.

Authors:  Smita Misra; Mack Hall; Gautam Chaudhuri
Journal:  J Parasitol       Date:  2005-12       Impact factor: 1.276

Review 4.  Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor.

Authors:  Mark E Hahn; Lenka L Allan; David H Sherr
Journal:  Biochem Pharmacol       Date:  2008-09-20       Impact factor: 5.858

5.  Alterations in three biomarkers (estrogen receptor, progesterone receptor and human epidermal growth factor 2) and the Ki67 index between primary and metastatic breast cancer lesions.

Authors:  Kimihito Fujii; Rie Watanabe; Takahito Ando; Junko Kousaka; Yukako Mouri; Miwa Yoshida; Tsuneo Imai; Shogo Nakano; Takashi Fukutomi
Journal:  Biomed Rep       Date:  2017-10-19

6.  Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene.

Authors:  Athena Starlard-Davenport; Beverly Lyn-Cook; Anna Radominska-Pandya
Journal:  Steroids       Date:  2007-09-29       Impact factor: 2.668

7.  Progesterone receptor-B regulation of insulin-like growth factor-stimulated cell migration in breast cancer cells via insulin receptor substrate-2.

Authors:  Yasir H Ibrahim; Sara A Byron; Xiaojiang Cui; Adrian V Lee; Douglas Yee
Journal:  Mol Cancer Res       Date:  2008-09       Impact factor: 5.852

8.  Proteomic snapshot of breast cancer cell cycle: G1/S transition point.

Authors:  Milagros J Tenga; Iulia M Lazar
Journal:  Proteomics       Date:  2013-01       Impact factor: 3.984

9.  Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study.

Authors:  João Conde; Susana N Silva; Ana P Azevedo; Valdemar Teixeira; Julieta Esperança Pina; José Rueff; Jorge F Gaspar
Journal:  BMC Cancer       Date:  2009-09-25       Impact factor: 4.430

10.  Functional analysis of familial Asp67Glu and Thr1051Ser BRCA1 mutations in breast/ovarian carcinogenesis.

Authors:  Malinee Pongsavee; Pimpicha Patmasiriwat; Grady F Saunders
Journal:  Int J Mol Sci       Date:  2009-09-24       Impact factor: 6.208
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