Literature DB >> 12548275

Computerized recruiting for clinical trials in real time.

Debra L Weiner1, Atul J Butte, Patricia L Hibberd, Gary R Fleisher.   

Abstract

STUDY
OBJECTIVE: Success of prospective studies, particularly in the emergency department, often depends on immediate identification of eligible patients to ensure timely sample collection and initiation of study interventions. We report use of a real-time automated notification system to identify potential patients for a clinical trial at the time of ED registration on the basis of information routinely collected. We hypothesize that the automated notification system improves the rate of investigator notification.
METHODS: We performed a prospective comparison of the notification rate by the automated notification system compared with that by ED clinicians.
RESULTS: In the 11 months before use of the automated notification system, the investigator was notified by ED staff for 56% of 61 potentially eligible patients. During 10 months of using the automated notification system, the investigator was paged by the automated notification system for 84% of 49 potentially eligible patients.
CONCLUSION: The automated notification system improves study investigator notification. Use requires online linked registration, a database, and paging systems. The automated notification system is a potentially valuable tool in the recruitment of patients for clinical trials.

Entities:  

Mesh:

Year:  2003        PMID: 12548275     DOI: 10.1067/mem.2003.52

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN: 0196-0644            Impact factor:   5.721


  28 in total

1.  The design and implementation of an open-source, data-driven cohort recruitment system: the Duke Integrated Subject Cohort and Enrollment Research Network (DISCERN).

Authors:  Jeffrey M Ferranti; William Gilbert; Jonathan McCall; Howard Shang; Tanya Barros; Monica M Horvath
Journal:  J Am Med Inform Assoc       Date:  2011-09-23       Impact factor: 4.497

2.  Efficacy and cost-effectiveness of an automated screening algorithm in an inpatient clinical trial.

Authors:  Catherine C Beauharnais; Mary E Larkin; Adrian H Zai; Emily C Boykin; Jennifer Luttrell; Deborah J Wexler
Journal:  Clin Trials       Date:  2012-02-03       Impact factor: 2.486

3.  Development of an electronic health record-based Clinical Trial Alert system to enhance recruitment at the point of care.

Authors:  Peter J Embi; Anil Jain; Jeffrey Clark; C Martin Harris
Journal:  AMIA Annu Symp Proc       Date:  2005

Review 4.  Recruiting participants for injury studies in emergency departments.

Authors:  Denise Kendrick; Ronan Lyons; Nicola Christie; Elizabeth Towner; Jonathan Benger; Lindsay Groom; Frank Coffey; Phillip Miller; Rachel Murphy
Journal:  Inj Prev       Date:  2007-04       Impact factor: 2.399

5.  Challenges of recruiting farm injury study participants through hospital emergency departments.

Authors:  Lesley Day; John Langley; Voula Stathakis; Rory Wolfe; Malcolm Sim; Don Voaklander; Joan Ozanne-Smith
Journal:  Inj Prev       Date:  2007-04       Impact factor: 2.399

6.  Enhancing an existing clinical information system to improve study recruitment and census gathering efficiency.

Authors:  Flory L Nkoy; Doug Wolfe; Joseph W Hales; Gena Lattin; Maryann Rackham; Christopher G Maloney
Journal:  AMIA Annu Symp Proc       Date:  2009-11-14

7.  Accelerating Biopharmaceutical Development in the Decade of Health Information Technology: Applications of EHRs for outcomes research and clinical trials recruitment.

Authors:  Michael I Lieberman; Peter Embi; Thomas N Ricciardi; Kevin Tabb
Journal:  Biotechnol Healthc       Date:  2005-08

8.  Easily configured real-time CPOE Pick Off Tool supporting focused clinical research and quality improvement.

Authors:  Benjamin P Rosenbaum; Nikolay Silkin; Randolph A Miller
Journal:  J Am Med Inform Assoc       Date:  2013-11-28       Impact factor: 4.497

9.  Using real-time alerts for clinical trials: Identifying potential study subjects.

Authors:  E Chow; M Zuberi; R Seto; S Hota; E N Fish; D Morra
Journal:  Appl Clin Inform       Date:  2011-11-16       Impact factor: 2.342

10.  Design and evaluation of a multimedia electronic patient record "oncoflow" with clinical workflow assistance for head and neck tumor therapy.

Authors:  Jens Meier; Andreas Boehm; Anne Kielhorn; Andreas Dietz; Stefan Bohn; Thomas Neumuth
Journal:  Int J Comput Assist Radiol Surg       Date:  2014-02-27       Impact factor: 2.924

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