Literature DB >> 12548156

Phenytoin decreases the blood concentrations of sirolimus in a liver transplant recipient: a case report.

Jonathan A Fridell1, Ashok Kumar B Jain, Kusum Patel, Mohamed Virji, K N Rao, John J Fung, Raman Venkataramanan.   

Abstract

This report documents that coadministration of phenytoin leads to decreased blood concentrations and area under the blood concentration-time curve of sirolimus in a liver transplant patient. It is essential to monitor the blood concentrations of sirolimus and adjust the sirolimus dosage when phenytoin administration begins or ends.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12548156     DOI： 10.1097/00007691-200302000-00019

Source DB:  PubMed          Journal:  Ther Drug Monit        ISSN： 0163-4356            Impact factor:   3.681


  5 in total

1.  Phenytoin-induced reduction in sirolimus levels.

Authors:  Duane Bates; Kelly W Burak; Carla S Coffin; Tammy Ying; Echo-Marie Enns
Journal:  Can J Hosp Pharm       Date:  2011-07

2.  What counts in data mining?

Authors:  Manfred Hauben; Vaishali K Patadia; David Goldsmith
Journal:  Drug Saf       Date:  2006       Impact factor: 5.606

3.  A comprehensive review of immunosuppression used for liver transplantation.

Authors:  Sandeep Mukherjee; Urmila Mukherjee
Journal:  J Transplant       Date:  2009-07-16

4.  Large-scale identification and analysis of suppressive drug interactions.

Authors:  Murat Cokol; Zohar B Weinstein; Kaan Yilancioglu; Murat Tasan; Allison Doak; Dilay Cansever; Beste Mutlu; Siyang Li; Raul Rodriguez-Esteban; Murodzhon Akhmedov; Aysegul Guvenek; Melike Cokol; Selim Cetiner; Guri Giaever; Ivan Iossifov; Corey Nislow; Brian Shoichet; Frederick P Roth
Journal:  Chem Biol       Date:  2014-04-03

Review 5.  Immunotherapy in elderly transplant recipients: a guide to clinically significant drug interactions.

Authors:  Dirk R J Kuypers
Journal:  Drugs Aging       Date:  2009       Impact factor: 3.923
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.