| Literature DB >> 12547603 |
Abstract
Immunostimulating reconstituted influenza virosomes (IRIVs) are a liposomal carrier system. Influenza hemagglutinin and neuraminidase are intercalated into the lipid bilayer and give the IRIVs their fusogenic activity. The system is already registered for human use and allows a specific targetting of antigens to a cellular or a humoral immune response. IRIVs are able to deliver proteins, RNA/DNA, peptides and mimetics to immunocompetent cells.Entities:
Mesh:
Substances:
Year: 2003 PMID: 12547603 DOI: 10.1016/s0264-410x(02)00541-8
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641