Literature DB >> 12543460

Cytokines regulate c-Met expression in cultured astrocytes.

Kenji Shimazaki1, Kazunari Yoshida, Yuji Hirose, Hisatsugu Ishimori, Makoto Katayama, Takeshi Kawase.   

Abstract

We investigated c-Met expression in cultured astrocytes and their regulation by cytokines. Immunocytochemistry revealed that c-Met was expressed in cultured astrocytes. Western blotting revealed that acidic and basic fibroblast growth factor (FGF) enhanced and hepatocyte growth factor (HGF) reduced c-Met expression. Reverse transcription-polymerase chain reaction revealed that FGFs and HGF enhanced c-met expression. These findings suggest that c-Met expressed in astrocytes may have important roles during the nervous system regeneration.

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Year:  2003        PMID： 12543460     DOI： 10.1016/s0006-8993(02)03975-6

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  6 in total

1.  Experimental investigation of HGF inhibiting glial scar in vitro.

Authors:  Cheng Liu; Zu-ze Wu; Cui-li Shu; Ding-feng Li; Yan-jun Zeng; Qiu Cui; Wei-hao Jiang
Journal:  Cell Mol Neurobiol       Date:  2010-11-13       Impact factor: 5.046

2.  In vitro and in vivo potentiating the cytotoxic effect of radiation on human U251 gliomas by the c-Met antisense oligodeoxynucleotides.

Authors:  Sheng-hua Chu; Zhi-an Zhu; Xian-hou Yuan; Zhi-qiang Li; Pu-cha Jiang
Journal:  J Neurooncol       Date:  2006-04-29       Impact factor: 4.130

3.  Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells.

Authors:  L Xu; M B Nilsson; P Saintigny; T Cascone; M H Herynk; Z Du; P G Nikolinakos; Y Yang; L Prudkin; D Liu; J J Lee; F M Johnson; K-K Wong; L Girard; A F Gazdar; J D Minna; J M Kurie; I I Wistuba; J V Heymach
Journal:  Oncogene       Date:  2010-02-15       Impact factor: 9.867

4.  The autism risk genes MET and PLAUR differentially impact cortical development.

Authors:  Kathie L Eagleson; Daniel B Campbell; Barbara L Thompson; Mica Y Bergman; Pat Levitt
Journal:  Autism Res       Date:  2010-12-03       Impact factor: 5.216

5.  Over-expression of Metastasis-associated in Colon Cancer-1 (MACC1) Associates with Better Prognosis of Gastric Cancer Patients.

Authors:  Shao-Hua Ge; Xiao-Jiang Wu; Xiao-Hong Wang; Xiao-Fang Xing; Lian-Hai Zhang; Yu-Bing Zhu; Hong Du; Bin Dong; Ying Hu; Jia-Fu Ji
Journal:  Chin J Cancer Res       Date:  2011-06       Impact factor: 5.087

6.  Synaptic and extrasynaptic location of the receptor tyrosine kinase met during postnatal development in the mouse neocortex and hippocampus.

Authors:  Kathie L Eagleson; Teresa A Milner; Zhihui Xie; Pat Levitt
Journal:  J Comp Neurol       Date:  2013-10-01       Impact factor: 3.215
  6 in total

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