| Literature DB >> 125432 |
L E Hicks, J D Maser, G G Gallup, P H Edson.
Abstract
Small doses of morphine, within the range of 0.02 mg/kg to 10.15 mg/kg were administered to chickens (Gallus gallus) and the effect on the fear-based tonic immobility (TI) response determined. All doses at and above 0.13 mg/kg enhanced the TI response significantly above the levels produced for the 0.2 mg/kg dose and the distilled water control group. Administration of a single large dose of p-chlorophenylalanine prevented the morphine-induced enhancement of TI. It was suggested that serotonin systems mediate morphine effects on tonic immobility in chickens.Entities:
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Year: 1975 PMID： 125432 DOI： 10.1007/bf00428825
Source DB: PubMed Journal: Psychopharmacologia