Literature DB >> 125429

Failure of antiserotonergic agents to modify levallorphan-induced stereotypy in rats.

K C Phillips, S R Wray.   

Abstract

The possibilty that the stereotypic behaviour induced by levallorphan, a narcotic antagonist, might be influenced by a serotonergic system was examined. Two antiserotonergic agents, methysergide and parachlorophenylalanine, failed to modify such stereotypy implying that serotonin is not involved. It is suggested that dopamine might be the principle mediator of this behaviour.

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Year:  1975        PMID： 125429     DOI： 10.1007/bf00428934

Source DB:  PubMed          Journal:  Psychopharmacologia


  19 in total

1.  Biochemical observations on LSD-25 and Deseril.

Authors:  W DOEPFNER
Journal:  Experientia       Date:  1962-06-15

2.  Evidence of catecholamine mediation in the "aberrant" behaviour induced by lysergic acid diethylamide (LSD) in the rat.

Authors:  A K Dixon
Journal:  Experientia       Date:  1968-07-15

3.  Aminergic mechanisms in corpus striatum and amphetamine-induced stereotyped behaviour.

Authors:  R L Fog; A Randrup; H Pakkenberg
Journal:  Psychopharmacologia       Date:  1967

4.  Role of brain noradrenaline in morphine-induced stereotyped behaviour.

Authors:  I H Ayhan; A Randrup
Journal:  Psychopharmacologia       Date:  1972

5.  The behavioural effects of levallorphan, cyprenorphine (M285) and amphetamine on repeated Y-maze performance in rats.

Authors:  S R Wray; A Cowan
Journal:  Psychopharmacologia       Date:  1971

6.  Direct chemical stimulation of dopaminergic mechanisms in the neostriatum of the rat.

Authors:  U Ungerstedt; L L Butcher; S G Butcher; N E Andén; K Fuxe
Journal:  Brain Res       Date:  1969-07       Impact factor: 3.252

7.  Apomorphine-induced aggression in the rat.

Authors:  G M McKenzie
Journal:  Brain Res       Date:  1971-11       Impact factor: 3.252

8.  The effects of p-chlorophenylalanine, a serotonin depletor, on avoidance acquisition, pain sensitivity and related behavior in the rat.

Authors:  S S Tenen
Journal:  Psychopharmacologia       Date:  1967

9.  Neuroleptic action of quaternary chlorpromazine and related drugs injected into various brain areas in rats.

Authors:  R L Fog; A Randrup; H Pakkenberg
Journal:  Psychopharmacologia       Date:  1968

10.  Tryptophan hydroxylase inhibition: the mechanism by which p-chlorophenylalanine depletes rat brain serotonin.

Authors:  E Jéquier; W Lovenberg; A Sjoerdsma
Journal:  Mol Pharmacol       Date:  1967-05       Impact factor: 4.436
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  2 in total

1.  Intracranial reward after Lilly 110140 (fluoxetine HCl): evidence for an inhibitory role for serotonin.

Authors:  R J Katz; B J Carroll
Journal:  Psychopharmacology (Berl)       Date:  1977-01-31       Impact factor: 4.530

2.  Backward walking and circling: behavioural responses induced by drug treatments which cause simultaneous release of catecholamines and 5-hydroxytryptamine.

Authors:  G Curzon; J C Fernando; A J Lees
Journal:  Br J Pharmacol       Date:  1979-08       Impact factor: 8.739
  2 in total

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