Literature DB >> 12539875

Response of F344 rats to inhalation of subclinical levels of sarin: exploring potential causes of Gulf War illness.

R F Henderson1, E B Barr, W B Blackwell, C R Clark, C A Conn, R Kalra, T H March, M L Sopori, Y Tesfaigzi, M G Ménache, D C Mash, K Dokladny, W Kozak, A Kozak, M Wachulec, K Rudolph, M J Kluger, S P Singh, S Razani-Boroujerdi, R J Langley.   

Abstract

Subclinical, repeated exposures of F344 rats to sarin resulted in brain alterations in densities of chlonergic receptor subtypes that may be associated with memory loss and cognitive dysfunction. The exposures also depressed the immune system. The rat appears to be a good model for studying the effects of subclinical exposure to a nerve gas.

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Year:  2001        PMID： 12539875     DOI： 10.1191/0748233701th105oa

Source DB:  PubMed          Journal:  Toxicol Ind Health        ISSN： 0748-2337            Impact factor:   2.273


  12 in total

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3.  All-Cause Mortality Among US Veterans of the Persian Gulf War: 13-Year Follow-up.

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4.  Mortality in US Army Gulf War veterans exposed to 1991 Khamisiyah chemical munitions destruction.

Authors:  Tim A Bullman; Clare M Mahan; Han K Kang; William F Page
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5.  Trends in brain cancer mortality among U.S. Gulf War veterans: 21 year follow-up.

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7.  Perfusion deficit to cholinergic challenge in veterans with Gulf War Illness.

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8.  Acetylcholinesterase inhibitors and Gulf War illnesses.

Authors:  Beatrice Alexandra Golomb
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9.  Brain Correlates of Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI).

Authors:  Lisa M James; Brian E Engdahl; Arthur C Leuthold; Apostolos P Georgopoulos
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10.  Epigenetic impacts of stress priming of the neuroinflammatory response to sarin surrogate in mice: a model of Gulf War illness.

Authors:  David G Ashbrook; Benjamin Hing; Lindsay T Michalovicz; Kimberly A Kelly; Julie V Miller; Wilfred C de Vega; Diane B Miller; Gordon Broderick; James P O'Callaghan; Patrick O McGowan
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