Literature DB >> 12535873

A model for temporal heterogeneities of tumor blood flow.

Francesco Mollica1, Rakesh K Jain, Paolo A Netti.   

Abstract

Tumor blood flow (TBF) plays a fundamental role in tumor growth and treatment, and is characterized by spatial and temporal heterogeneities. Here we show that the interstitial fluid pressure (IFP), which is higher in tumoral tissue than in normal tissue, coupled with the tumor microvascular pressure (MVP) and the higher permeability of tumoral vessels, can explain the sustained oscillatory behavior of TBF, observed in vivo.

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Year:  2003        PMID： 12535873     DOI： 10.1016/s0026-2862(02)00012-2

Source DB:  PubMed          Journal:  Microvasc Res        ISSN： 0026-2862            Impact factor:   3.514


  14 in total

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