Literature DB >> 12535263

Ganciclovir-resistant cytomegalovirus encephalitis in a bone marrow transplant recipient.

J E Julin1, J H van Burik, W Krivit, C Webb, C J Holman, H B Clark, H H Balfour.   

Abstract

A 20-year-old patient, who received a bone marrow transplant in order to treat metachromatic leukodystrophy (MLD), succumbed to cytomegalovirus (CMV) encephalitis. After CMV viremia developed, the patient received ganciclovir, but he was switched to foscarnet when ganciclovir resistance was suspected. Foscarnet was discontinued because of concern about its potential central nervous system toxicity. Autopsy samples of brain and cerebrospinal fluid contained CMV DNA with a UL97 mutation (M460V) known to confer ganciclovir resistance. No foscarnet resistance mutations were found.

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Year:  2002        PMID： 12535263     DOI： 10.1034/j.1399-3062.2002.02005.x

Source DB:  PubMed          Journal:  Transpl Infect Dis        ISSN： 1398-2273            Impact factor:   2.228


  13 in total

1.  Ganciclovir-resistant cytomegalovirus encephalitis in a hematopoietic stem cell transplant recipient.

Authors:  Ferhat Arslan; Fehmi Tabak; Emin Avşar; Kenan Midilli; Ali Mert; Resat Ozaras; Teoman Soysal; Recep Ozturk; Burhan Ferhanoglu
Journal:  J Neurovirol       Date:  2010-03       Impact factor: 2.643

2.  A fatal case of cytomegalovirus ventriculoencephalitis in a mycosis fungoides patient who received multiple umbilical cord blood cell transplantations.

Authors:  Toshihiro Matsukawa; Hideki Goto; Kenta Takahashi; Shinsuke Asanuma; Atsushi Yasumoto; Mutsumi Takahata; Akio Shigematsu; Tomoyuki Endo; Junji Tanaka; Satoshi Hashino; Shinya Tanaka; Masahiro Imamura
Journal:  Int J Hematol       Date:  2012-01-20       Impact factor: 2.490

3.  Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis.

Authors:  Jocelyne Piret; Manuel Schibler; Van Dung Pham; Sébastien Hantz; Federica Giannotti; Stavroula Masouridi-Levrat; Laurent Kaiser; Nathalie Goyette; Sophie Alain; Rong Shi; Guy Boivin
Journal:  J Infect Dis       Date:  2019-09-13       Impact factor: 5.226

4.  Detection of donor-derived CMV-specific T cells in cerebrospinal fluid in a case of CMV meningoencephalitis after cord blood stem cell transplantation.

Authors:  Kazuhiro Ikegame; Ruri Kato; Tatsuya Fujioka; Masaya Okada; Katsuji Kaida; Shinichi Ishii; Satoshi Yoshihara; Takayuki Inoue; Kyoko Taniguchi; Hiroya Tamaki; Toshihiro Soma; Hiroyasu Ogawa
Journal:  Int J Hematol       Date:  2012-12-29       Impact factor: 2.490

Review 5.  Antiviral drug resistance: mechanisms and clinical implications.

Authors:  Lynne Strasfeld; Sunwen Chou
Journal:  Infect Dis Clin North Am       Date:  2010-06       Impact factor: 5.982

6.  How evolution of mutations conferring drug resistance affects viral dynamics and clinical outcomes of cytomegalovirus-infected hematopoietic cell transplant recipients.

Authors:  Kathryn L Springer; Sunwen Chou; Shaobing Li; Roger H Giller; Ralph Quinones; James E Shira; Adriana Weinberg
Journal:  J Clin Microbiol       Date:  2005-01       Impact factor: 5.948

7.  Cytomegalovirus ventriculoencephalitis after unrelated double cord blood stem cell transplantation with an alemtuzumab-containing preparative regimen for Philadelphia-positive acute lymphoblastic leukemia.

Authors:  Seok Lee; Si-Hyun Kim; Su-Mi Choi; Dong-Gun Lee; Sung-Yong Kim; Jong-Wook Lee; Woo-Sung Min; Wan-Shik Shin; Chun-Choo Kim
Journal:  J Korean Med Sci       Date:  2010-03-19       Impact factor: 2.153

8.  Impact of delirium on distress, health-related quality of life, and cognition 6 months and 1 year after hematopoietic cell transplant.

Authors:  James R Basinski; Catherine M Alfano; Wayne J Katon; Karen L Syrjala; Jesse R Fann
Journal:  Biol Blood Marrow Transplant       Date:  2010-01-25       Impact factor: 5.742

9.  Temporal and spatial compartmentalization of drug-resistant cytomegalovirus (CMV) in a child with CMV meningoencephalitis: implications for sampling in molecular diagnosis.

Authors:  Pierre Frange; David Boutolleau; Marianne Leruez-Ville; Fabien Touzot; Guilhem Cros; Sebastien Heritier; Despina Moshous; Benedicte Neven; Alain Fischer; Stephane Blanche
Journal:  J Clin Microbiol       Date:  2013-10-09       Impact factor: 5.948

10.  Differential outcome of neurological HCMV infection in two hematopoietic stem cell transplant recipients.

Authors:  Anna Amelia Colombo; Giovanna Giorgiani; Vanina Rognoni; Paola Villani; Milena Furione; Mario Regazzi Bonora; Emilio Paolo Alessandrino; Marco Zecca; Fausto Baldanti
Journal:  BMC Infect Dis       Date:  2012-10-03       Impact factor: 3.090
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