Literature DB >> 12531866

Rare genetic mutations shed light on the pathogenesis of Parkinson disease.

Ted M Dawson1, Valina L Dawson.   

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Year:  2003        PMID： 12531866      PMCID： PMC151882          DOI： 10.1172/JCI17575

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  65 in total

1.  Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis.

Authors:  Y Tanaka; S Engelender; S Igarashi; R K Rao; T Wanner; R E Tanzi; A Sawa; V L Dawson; T M Dawson; C A Ross
Journal:  Hum Mol Genet       Date:  2001-04-15       Impact factor: 6.150

2.  Familial atypical progressive supranuclear palsy associated with homozigosity for the delN296 mutation in the tau gene.

Authors:  P Pastor; E Pastor; C Carnero; R Vela; T García; G Amer; E Tolosa; R Oliva
Journal:  Ann Neurol       Date:  2001-02       Impact factor: 10.422

3.  Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity.

Authors:  Y Imai; M Soda; R Takahashi
Journal:  J Biol Chem       Date:  2000-11-17       Impact factor: 5.157

4.  Neuropathology in mice expressing human alpha-synuclein.

Authors:  H van der Putten; K H Wiederhold; A Probst; S Barbieri; C Mistl; S Danner; S Kauffmann; K Hofele; W P Spooren; M A Ruegg; S Lin; P Caroni; B Sommer; M Tolnay; G Bilbe
Journal:  J Neurosci       Date:  2000-08-15       Impact factor: 6.167

5.  Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.

Authors:  R Krüger; W Kuhn; T Müller; D Woitalla; M Graeber; S Kösel; H Przuntek; J T Epplen; L Schöls; O Riess
Journal:  Nat Genet       Date:  1998-02       Impact factor: 38.330

6.  Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.

Authors:  M H Polymeropoulos; C Lavedan; E Leroy; S E Ide; A Dehejia; A Dutra; B Pike; H Root; J Rubenstein; R Boyer; E S Stenroos; S Chandrasekharappa; A Athanassiadou; T Papapetropoulos; W G Johnson; A M Lazzarini; R C Duvoisin; G Di Iorio; L I Golbe; R L Nussbaum
Journal:  Science       Date:  1997-06-27       Impact factor: 47.728

7.  Familial aggregation of Parkinson's disease in Iceland.

Authors:  S Sveinbjörnsdottir; A A Hicks; T Jonsson; H Pétursson; G Guğmundsson; M L Frigge; A Kong; J R Gulcher; K Stefansson
Journal:  N Engl J Med       Date:  2000-12-14       Impact factor: 91.245

8.  Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1.

Authors:  Y Zhang; J Gao; K K Chung; H Huang; V L Dawson; T M Dawson
Journal:  Proc Natl Acad Sci U S A       Date:  2000-11-21       Impact factor: 11.205

9.  Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain.

Authors:  P J Kahle; M Neumann; L Ozmen; V Muller; H Jacobsen; A Schindzielorz; M Okochi; U Leimer; H van Der Putten; A Probst; E Kremmer; H A Kretzschmar; C Haass
Journal:  J Neurosci       Date:  2000-09-01       Impact factor: 6.167

10.  Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36.

Authors:  E M Valente; A R Bentivoglio; P H Dixon; A Ferraris; T Ialongo; M Frontali; A Albanese; N W Wood
Journal:  Am J Hum Genet       Date:  2001-03-07       Impact factor: 11.025
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  54 in total

Review 1.  Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders.

Authors:  Mark P Mattson
Journal:  Neuromolecular Med       Date:  2003       Impact factor: 3.843

Review 2.  Neurodegeneration: what is it and where are we?

Authors:  Serge Przedborski; Miquel Vila; Vernice Jackson-Lewis
Journal:  J Clin Invest       Date:  2003-01       Impact factor: 14.808

3.  Elucidating the pathogenesis of schizophrenia.

Authors:  Akira Sawa; Atsushi Kamiya
Journal:  BMJ       Date:  2003-09-20

Review 4.  Regulation of Parkin E3 ubiquitin ligase activity.

Authors:  Helen Walden; R Julio Martinez-Torres
Journal:  Cell Mol Life Sci       Date:  2012-04-19       Impact factor: 9.261

5.  The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax.

Authors:  Bethann N Johnson; Alison K Berger; Giuseppe P Cortese; Matthew J Lavoie
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-29       Impact factor: 11.205

Review 6.  Redefining Parkinson's disease research using induced pluripotent stem cells.

Authors:  Jiali Pu; Houbo Jiang; Baorong Zhang; Jian Feng
Journal:  Curr Neurol Neurosci Rep       Date:  2012-08       Impact factor: 5.081

Review 7.  Endoplasmic reticulum stress: cell life and death decisions.

Authors:  Chunyan Xu; Beatrice Bailly-Maitre; John C Reed
Journal:  J Clin Invest       Date:  2005-10       Impact factor: 14.808

Review 8.  Neurodegenerative disorders: Parkinson's disease and Huntington's disease.

Authors:  S M Hague; S Klaffke; O Bandmann
Journal:  J Neurol Neurosurg Psychiatry       Date:  2005-08       Impact factor: 10.154

9.  DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase.

Authors:  Eva Andres-Mateos; Celine Perier; Li Zhang; Beatrice Blanchard-Fillion; Todd M Greco; Bobby Thomas; Han Seok Ko; Masayuki Sasaki; Harry Ischiropoulos; Serge Przedborski; Ted M Dawson; Valina L Dawson
Journal:  Proc Natl Acad Sci U S A       Date:  2007-08-31       Impact factor: 11.205

Review 10.  Programmed cell death in Parkinson's disease.

Authors:  Katerina Venderova; David S Park
Journal:  Cold Spring Harb Perspect Med       Date:  2012-08-01       Impact factor: 6.915
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